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Fig. 2 | BMC Pregnancy and Childbirth

Fig. 2

From: Identification and validation of diagnostic biomarkers for intrahepatic cholestasis of pregnancy based on untargeted and targeted metabolomics analyses of urine metabolite profiles

Fig. 2

Multivariate statistical analysis of metabolomics between normal and intrahepatic cholestasis of pregnancy (ICP) samples. Orthogonal partial-least squares discrimination analysis (OPLS-DA) score plot derived from UHPLC-Q-TOF/MS-based metabolomics analysis between normal (blue squares) and ICP (green circles) samples. (A) Positive ion mode; (B) Negative ion mode. Statistical validation of the OPLS-DA model by permutation testing. (C) Positive ion mode; (D) Negative ion mode. Q2, predictive ability; R2Y, goodness of fit

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