Fig. 2From: Identification and validation of diagnostic biomarkers for intrahepatic cholestasis of pregnancy based on untargeted and targeted metabolomics analyses of urine metabolite profilesMultivariate statistical analysis of metabolomics between normal and intrahepatic cholestasis of pregnancy (ICP) samples. Orthogonal partial-least squares discrimination analysis (OPLS-DA) score plot derived from UHPLC-Q-TOF/MS-based metabolomics analysis between normal (blue squares) and ICP (green circles) samples. (A) Positive ion mode; (B) Negative ion mode. Statistical validation of the OPLS-DA model by permutation testing. (C) Positive ion mode; (D) Negative ion mode. Q2, predictive ability; R2Y, goodness of fitBack to article page