Table 4 Comparison of our study with previously (recently) published systematic reviews and meta-analyses
| Â | Bellos 2022Â [87] | Abu-Zaid 2022Â [88] | Our study | ||
|---|---|---|---|---|---|
Number of studies | 36 | 16 | 59 | ||
Number of patients | 10,659 | 7122 | 18,649 | ||
The design of studies included | RCTs | RCTs | RCTS | ||
Mode of birth throughout | CB | VB | CB and VB | ||
Total blood loss | Favor TXA | Moderate evidence | Favor TXA | Favor TXA | Moderate evidence |
Change in hemoglobin | Favor TXA | Moderate evidence | Favor TXA | Favor TXA (CB only) | Moderate evidence |
The occurrence rate of PPH | Favor TXA | Low evidence | Favor TXA | Favor TXA | Moderate for CB, High for VB |
Additional uterotonic agents | Favor TXA | Low evidence | Favor TXA | Favor TXA | Moderate for CB, High for VB |
Intraoperative blood loss | NR | NR | Favor TXA (CB only) | Moderate evidence | |
Post-operative blood loss | NR | NR | Favor TXA | Moderate for CB, High for VB | |
Occurrence of nausea and vomiting | NR | Not favor TXA | Not Favor TXA | High evidence | |
Incidence of hysterectomy | NR | NR | NS | High evidence | |