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Table 1 Univariate analysis of influencing factors of Clinical pregnancy

From: Development and validation of a nomogram model for predicting clinical pregnancy in endometriosis patients undergoing fresh embryo transfer

Characteristics

Total (n = 1630)

Unpregnancy (n = 931)

Pregnancy (n = 699)

P value

Female age(year)

33.0 [30.0;36.0]

34.0 [31.0;38.0]

32.0 [30.0;35.0]

<0.001*

Male age(year)

35.0 [31.0;38.0]

35.0 [32.0;40.0]

34.0 [31.0;37.0]

<0.001*

BMI(kg/m2), % (n)

   

0.375

 >24

82.1 (1339)

81.4 (758)

81.3 (581)

 

 ≤24

19.7 (291)

18.6 (173)

16.9 (118)

 

Type of infertility, % (n)

   

0.203

 Primary infertility

48.9 (797)

47.5 (442)

50.8 (355)

 

 Secondary infertility

51.1 (833)

52.5 (489)

49.2 (344)

 

ASRM stage, % (n)

   

<0.001*

 I/II

24.3 (396)

17.8 (166)

32.9 (230)

 

 III/IV

75.7 (1234)

82.2 (765)

67.1 (469)

 

Postoperative to IVF duration(year), % (n)

   

<0.001*

 ≤3

72.0 (1173)

63.1 (587)

83.8 (586)

 

 >3

28.0 (457)

36.9 (344)

16.2 (113)

 

COH protocol, % (n)

   

<0.001*

 GnRH-antagonist

38.4 (568)

42.5(396)

24.6 (172)

 

 GnRH-agonist

65.2 (1062)

57.5 (535)

75.4 (527)

 

Initial dose of Gn

200 [150;225]

225 [150;225]

188 [150;225]

<0.001*

Total dose of Gn

2700 [2175;3372]

2688 [2175;3300]

2700 [2144;3431]

0.283

Dosing days of Gn

12.0 [10.0;13.0]

11.0 [10.0;13.0]

12.0 [10.0;13.0]

<0.001*

Basal FSH (IU/L)

6.81 [5.73;8.29]

6.92 [5.79;8.43]

6.62 [5.66;8.02]

0.005 *

Basal LH (IU/L)

3.10 [2.30;4.20]

3.10 [2.30;4.20]

3.10 [2.30;4.20]

0.958

Basal E2 (pg/mL)

34.0 [25.0;47.0]

34.0 [25.0;47.0]

33.0 [24.0;46.0]

0.429

AFC

6.00 [4.00;7.00]

5.00 [3.00;7.00]

6.00 [5.00;8.00]

<0.001 *

AMH (μg/L)

1.71 [1.06;2.65]

1.54 [0.91;2.37]

2.02 [1.26;3.08]

<0.001*

FSH on HCG day (IU/L)

14.6 [11.7;18.0]

14.9 [12.1;18.5]

14.2 [11.1;17.3]

<0.001 *

E2 on HCG day (pg/mL)

1328 [773;1944]

1211 [724;1828]

1479 [861;2106]

<0.001*

LH on HCG day (IU/L)

1.20 [0.90;2.00]

1.30 [0.90;2.20]

1.10 [0.80;1.80]

<0.001*

P on HCG day (ng/mL)

0.47 [0.30;0.70]

0.46 [0.30;0.70]

0.49 [0.30;0.66]

0.849

Endometrial thickness on HCG day(mm)

11.0 [9.70;12.2]

11.0 [9.50;12.0]

11.0 [10.0;12.7]

<0.001 *

Fertilization, % (n)

   

0.113

 IVF

78.5 (1279)

77.0(717)

80.4 (562)

 

 ICSI

21.5 (351)

23.0 (214)

19.6 (137)

 

Number of oocytes retrieved

5.00 [4.00;7.00]

5.00 [3.00;7.00]

6.00 [4.00;7.00]

<0.001*

Number of high-quality cleavage embryos

3.00 [2.00;5.00]

3.00 [2.00;4.00]

4.00 [3.00;5.00]

<0.001 *

High-quality embryo rate, % (n/N)

81.4 (5843/7178)

80.2 (2978/3715)

82.7 (2865/3463)

0.371

Stage of embryos transferred, % (n)

   

0.088

Blastocyst

18.8 (307)

17.4 (162)

20.7 (145)

 

Cleavage

81.2 (1323)

82.6 (769)

79.3 (554)

 

Number of embryos transferred, % (n)

   

<0.001*

 1

34.8 (567)

43.5 (405)

23.2 (162)

 

 2

65.2 (1063)

56.5 (526)

76.8 (537)

 
  1. *P < 0.05
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BMC Pregnancy and Childbirth

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