Table 2 Levels of IGFBP-3/IGF-1/TGF-β1/VEGF in maternal blood of three groups

IGFBP-3 (ng/mL)

58.15 ± 15.95

45.42 ± 16.54

36.62 ± 9.10

35.22

0.000^**

①:②

0.003^**

①:③

0.000^**

②:③

0.000^**

IGF-1 (pg/mL)

1019.05 (367.05, 1700.73)

1497.16 (739.42, 1969.28)

2597.90 (2153.57, 3333.22)

39.80

0.000^**

①:②

0.263

①:③

0.000^**

②:③

0.000^**

TGF-β1 (pg/mL)

982.00 ± 342.81

495.65 ± 176.50

270.87 ± 74.53

74.535

0.000^**

①:②

0.000^**

①:③

0.000^**

②:③

0.000^**

VEGF (pg/mL)

42.11 (19.95, 94.33)

105.59 (37.22, 167.75)

171.28 (92.78, 217.28)

25.179

0.000^**

①:②

0.027^*

①:③

0.000^**

②:③

0.048^*