Table 6 The results of univariate and multivariate logistic regression tests in determining the relationship between addiction, lead concentrations in mother’s blood and umbilical cord blood with outcomes of meconium, hospitalization in NICU, respiratory problems, congenital anomalies and neonatal resuscitation

Meconium

Variables

Univariate logistic regression

Multivariate logistic regression

B

OR

95% CI

P value

B

OR

95% CI

P value

Lower Bound

Upper Bound

Lower Bound

Upper Bound

(Constant)

-2.25

0.1

00.1

Addiction

Yes

0.98

2.66

0.62

11.3

0.18

1.22

3.41

0.43

27.11

0.24

No

reference

Maternal blood lead (µg/dL)

0.03

1.03

0.97

1.09

0.25

Umbilical cord blood lead (µg/dL)

-2.21

0.1

0.95

1.11

0.001

-0.01

0.98

0.87

1.1

0.74

Hospitalization in NICU

Variables

Univariate logistic regression

Multivariate logistic regression

B

OR

95% CI

P value

B

OR

95% CI

P value

Lower Bound

Upper Bound

Lower Bound

Upper Bound

(Constant)

-2.64

0.07

< 0.001

Addiction

Yes

1.45

4.26

1.06

17.16

0.04

0.8

2.22

0.26

18.86

0.46

No

reference

Maternal blood lead (µg/dL)

0.06

1.06

1.03

1.1

0.02

0.16

1.17

0.99

1.39

0.06

Umbilical cord blood lead (µg/dL)

0.05

0.11

0.98

1.12

0.14

-0.17

0.83

0.68

1.03

0.09

Respiratory problems

Variables

Univariate logistic regression

Multivariate logistic regression

B

OR

95% CI

P value

B

OR

95% CI

P value

Lower Bound

Upper Bound

Lower Bound

Upper Bound

(Constant)

-2.38

0.09

0.001

Addiction

Yes

1.15

3.16

0.76

3.16

0.11

1.1

3.02

0.36

25.15

0.3

No

reference

Maternal blood lead (µg/dL)

0.03

0.09

0.98

1.03

0.18

0.003

1.003

0.91

1.09

0.95

Umbilical cord blood lead (µg/dL)

0.01

1.01

0.94

1.09

0.63

Congenital anomalies

Variables

Univariate logistic regression

Multivariate logistic regression

B

OR

95% CI

P value

B

OR

95% CI

P value

Lower Bound

Upper Bound

Lower Bound

Upper Bound

(Constant)

Addiction

Yes

17.67

4751

0

1.1

0.99

No

reference

Maternal blood lead (µg/dL)

-0.002

0.99

0.83

1.19

0.98

Umbilical cord blood lead (µg/dL)

-0.08

0.92

0.66

1.28

0.62

Neonatal resuscitation

Variables

Univariate logistic regression

Multivariate logistic regression

B

OR

95% CI

P value

B

OR

95% CI

P value

Lower Bound

Upper Bound

Lower Bound

Upper Bound

(Constant)

-2.83

0.05

< 0.0001

Addiction

Yes

1.58

4.88

0.95

24.97

0.056

1.52

4.58

0.46

44.99

0.19

No

reference

Maternal blood lead (µg/dL)

0.05

1.05

0.99

1.15

0.1

0.004

1.004

0.91

1.09

0.93

Umbilical cord blood lead (µg/dL)

0.03

1.03

0.95

1.11

0.42