Intertwin nuchal translucency difference predicts the chance of co-twin death after fetal reduction in dichorionic triplet pregnancies: a retrospective analysis study

Table 4 Logistic regression analysis of ultrasound measurements at 11–13⁺⁶ weeks

Variable	Group A1^a (n = 118)	Group A2^a (n = 16)	P value	Adjusted P value^†	Odds ratio (95% CI)
CRL difference (mm)	3.0 (1.7–6.0)	3.0 (1.0–6.0)	0.881	0.870	-
CRL discordance (%)	5.2 (2.8–10.3)	5.4 (1.3–10.4)	0.987	0.986	-
CRL discordance > 10%	30 (25.4)	4 (25.0)	0.971	0.979	-
NT difference (mm)	0.3 (0.2–0.7)	0.2 (0.1–0.5)	0.165	0.025	9.27 (1.32–65.18)
NT discordance (%)	22.6 (12.5–42.8)	15.6 (9.3–28.0)	0.135	0.045	1.04 (1.01–1.08)
Both NT < p95	104 (88.1)	14 (87.5)	-	-	-
One or both NT ≥ p95	9 (7.6)	2 (12.5)	0.999	0.999	-
One or both NT ≥ p99	5 (4.2)	0	0.832	0.946	-
AFV difference (mm)	4.0 (1.0–8.0)	4.0 (1.0–6.7)	0.384	0.498	-
AFV discordance (%)	14.0 (4.3–26.0)	15.3 (2.8–19.3)	0.472	0.633	-

Data are expressed as median (interquartile range) or n (%)
AFV Amniotic fluid volume, CI Confidence interval, CRL crown–rump length, NT Nuchal translucency thickness, p95 95^th percentile, p99 99^th percentile
^aExcluding patients without data on ultrasound measurements at 11–13 ⁺⁶ weeks
^†Adjusted for maternal age, parity, mode of conception, indication for fetal reduction, and gestation age at the time of fetal reduction

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