Table 3 Genes and their GO terms of the responsible variants for the preterm LBW prediction

Negative regulation of toll-like receptor signaling pathway

IRF4^a, NLRP6, PDPK1

AX-30019939, rs76318740, rs2666970^a

11.19

Antimicrobial humoral response

AZU1, DEFA4

AX-36710985, rs12460114

5.01

Cellular extravasation

AZU1, ITGA1

rs2456207, rs12460114, AX-15065431

4.69

Extracellular matrix organization

ITGA9, CRISPLD2, MADCAM1, NID1, TNR, ITGA1, SMOC2

rs2227163, AX-12439132, rs2171027, rs2456207, rs12599043, AX-30715297, rs6796546, rs3745925, AX-41915613, AX-15065431

3.73

Positive regulation of protein secretion

APBB1, EXPH5, PPID

rs8396, AX-11523840, rs3741048, AX-39132915

3.47

Cellular response to drug

RANBP1, RECQL5, KCNQ1, CAD

AX-33756771, rs79886149, rs3864884, rs72631384

2.69

Protein complex assembly

TCEB2, SLC9A3R2, HES1, PPID, IL2RB

rs2368048, rs8396, rs229489, rs4036, AX-40011429

2.67

Cellular response to insulin stimulus

CAPN10, INHBB, USF1, LPIN1, PDPK1

AX-13593741, rs76318740, rs117098832, AX-33691969, AX-39117777

0.10

Late viral transcription

USF1,MON1B

AX-39117777,AX-12559658

0.09

Chondroitin sulfate proteoglycan biosynthetic process

B3GAT1,ACPL2,CYTL1

AX-14133852,AX-41486923,rs6439996,rs75219147

0.09