Table 2 Genes and their GO terms of the responsible variants for the term LBW prediction
GO terms | Genes | Variants | The proportion of Importance score (%) |
|---|---|---|---|
Positive regulation of insulin secretion | PRKCE, GLUL, GHRL | rs117394235, rs17034641, rs75701130, AX-40988767, AX-30300885 | 8.47 |
Neurotransmitter uptake | SLC38A1, GLUL | AX-30300885, rs7971437 | 7.61 |
Positive regulation of positive chemotaxis | VEGFA, F7 | rs3093253, rs3025022, rs3025039 | 6.93 |
Positive regulation of epithelial cell proliferation | VEGFA, LAMB1, GLUL | rs20556, AX-30300885, rs3025039, rs3025022 | 5.87 |
Protein complex assembly | TCEB2, HES1, PPID, IL2RB | rs229489, rs4036, rs8396, rs2368048 | 5.68 |
Negative regulation of protein ubiquitination | N4BP1, NXN, PRKCE | AX-40988767, rs117329408, rs4968069, rs17034641, rs75701130 | 5.38 |
Response to estrogen | TPH2, F7, GHRL | rs3093253, rs41317118, rs117394235 | 4.52 |
Positive regulation of growth hormone secretion | KISS1, GHRL | rs11240694, rs117394235 | 4.26 |
Platelet activation | ITPR1, PRKCE, DGKD, PDPK1 | rs17034641, rs2307068, rs75701130, rs3749383, AX-40988767, rs882428, rs76318740 | 4.09 |
Positive regulation of cell adhesion | MIP, VEGFA, APBB1IP | AX-38792903, rs3025039, rs3025022, AX-30823381 | 4.02 |