Outcome | Measure | Definition |
---|---|---|
Primary outcome | Live birth | Birth of a breathing live-born infant with a heartbeat after 28 completed weeks of gestation |
Secondary outcomes | Clinical pregnancy | Presence of intrauterine gestation sacs at 30–35 days after embryo transfer |
 | Ongoing pregnancy | Presence of a fetal pole with pulsation at 8–10 weeks of gestation |
 | Early miscarriage | Miscarriage within 12 weeks of embryo transfer |
 | Late miscarriage | Miscarriage between 12 and 28 weeks of embryo transfer |
 | Cumulative live birth rate | Birth of a live-born infant conceived within three embryo transfers. Each time a single embryo is transferred is considered. |
 | Ectopic pregnancy | Pregnancy outside the uterine cavity |
 | Time to pregnancy | Time interval between the oocyte retrieval date and clinical pregnancy |