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Table 3 Treatments performed by respondents (in%) with recommendations of the Dutch and ESHRE guideline

From: Identifying discrepancies between clinical practice and evidence-based guideline in recurrent pregnancy loss care, a tool for clinical guideline implementation

 

Number of respondents

Respondents (%)

Dutch guideline

ESHRE guideline

General advice

Smoking cessation

Alcohol cessation

Weight loss

Folic acid

Vitamin D

310/325

217/325

254/325

290/325

142/325

95

67

78

89

44

Recommended

Yes

Yes

Yes

*

No

Recommended

Yes

Yes

Yes

Yes+

Yes+

Genetic factors

Genetic counselling

PGT

184/318

76/318

58

24

Recommended

Recommended

Uterine factors

Septum resection

37/304

12

Not recommended

Not recommended

Endocrine antibodies (TPO)

26/307

9

Not recommended

Not recommended

Antiphospholipid syndrome

190/318

60

Recommended

Recommended

Thrombophilia

137/313

44

Not recommended

Not recommended

Unexplained RPL

Progesteron

hMG

IVF

HCG

Thyroxine

Corticosteroids

IVIG

Intralipids

LMWH

Aspirin

Donor insemination

Oocyte donation

Endometrium scratching

Cross border care referral

51/303

1/303

2/303

3/303

4/303

3/303

0/303

0/303

12/303

38/303

0/303

0/303

1/303

23/303

17

0

1

1

1

1

0

0

4

13

0

0

0

8

Not recommended

Not recommended

  1. * Not indicated
  2. + Not recommended in the context of improving live birth in RPL couples, but for general health purposes