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Table 4 Univariate and multivariate analysis to examine the risk factor of severe PPHa in pregnant women with placenta previa

From: Clinical significance of retained products of conception in placenta previa: a retrospective analysis

 

Univariate analysis

Multivariate analysis

Odds ratio (95% Confidence interval)

p-value

Odds ratio (95% Confidence interval)

p-value

Maternal age

  > 35 years vs. < 35 years

1.19

(0.55–2.59)

0.66

   

Gestational age at delivery

  > 37 weeks vs. < 37 weeks

1.03

(0.46–2.32)

0.94

   

Parity

 Primipara vs Multipara

0.43

(0.19–0.98)

0.04

0.95

(0.27–3.33)

0.93

In vitro fertilization pregnancy

 Yes vs. No

0.80

(0.23–2.78)

0.73

   

Tocolytic agent use

 Yes vs. No

1.26

(0.58–2.74)

0.56

   

Warning bleedingb

 Yes vs. No

1.40

(0.62–3.16)

0.41

   

Prior CS

 Yes vs. No

9.23

(4.02–21.20)

 < 0.01

4.71

(1.29–17.13)

0.02

The mode of cesarean section

 Emergency vs. Elective

0.98

(0.38–2.51)

0.96

   

The classification of placenta previa

 Major previac vs. Minor previad

11.35

(3.35–38.38)

 < 0.01

7.50

(1.98–28.43)

 < 0.01

Main location of placenta

 Anterior wall vs. Posterior wall

3.44

(1.40–8.44)

 < 0.01

1.83

(0.56–6.00)

0.32

Placenta accreta spectrum

 Yes vs. No

16.47

(4.66–58.26)

 < 0.01

2.53

(0.39–16.46)

0.33

Prior endometrial curettage

 Yes vs. No

0.71

(0.28–1.82)

0.48

   

Retained products of conception

 Yes vs. No

29.70

(11.23–78.55)

 < 0.01

13.26

(3.61–48.63)

 < 0.01

  1. PPH postpartum hemorrhage, CS cesarean section
  2. aSevere PPH was defined as > 1000 ml of blood loss within 24 h of CS
  3. bWarning bleeding was defined as painless genital bleeding from the placenta
  4. cMajor previa was defined as the placenta that covered the internal cervical os
  5. dMinor previa was defined as the leading edge of the placenta, which was located within 2 cm from internal cervical OS but did not cover the cervical os