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Table 5 Postpartum hemorrhage related outcomes

From: Effect of preoperative prophylactic intravenous tranexamic acid on perioperative blood loss control in patients undergoing cesarean delivery: a systematic review and meta-analysis

Randomized Controlled Trial (RCT)

Study

Blood Loss (mL)a

Blood Loss (mL)b

Blood Loss (mL)c

Blood Transfusion (n)

Hemoglobin Change (g/dL)

TXA

Control

TXA

Control

TXA

Control

TXA

Control

TXA

Control

Ali Movafegh[15]

262.5 ± 39.6

404.7 ± 94.4

67.1 ± 6.5

141.0 ± 33.9

    

1.0 ± 0.4

1.8 ± 0.7

H. Abdel-Aleem[16]

    

241.61 ± 126.02

510.70 ± 144.52

  

0.48 ± 0.87

1.42 ± 1.16

Mehmet B. Sentu ̈rk

        

1.11 ± 0.62

1.27 ± 0.66

Anuradha Ghosh

367.8 ± 36.77

627.8 ± 95.15

48.06 ± 8.202

76.02 ± 6.209

    

1.16 ± 0.316

1.83 ± 0.372

Haitham Torky

591.55 ± 162.08

678.37 ± 171.49

    

3/60

9/60

  

Abd El-Naser Abd El-Gaber

387.68 ± 93.05

560.79 ± 107.46

159.16 ± 50.95*

232.68 ± 65.18*

546.84 ± 106.13#

793.99 ± 141.21#

  

0.475 ± 0.23

1.06 ± 0.31

Forozan Milani

509.5 ± 208.7

649.9 ± 234.1

42.3 ± 21.75

63.2 ± 48.84

551.8 ± 207.8

713.1 ± 233.1

    

Zahra Naeiji

391.1 ± 67.4

523.8 ± 153.4

56.0 ± 21.9*

61.6 ± 30.6*

  

5/100

13/100

  

Amr H. Yehia

369.5 ± 198

606.8 ± 193

85.0 ± 30.7*

130.8 ± 49.3*

454.5 ± 201#

737.6 ± 217#

    

Cohort Studies

Upasana Goswami[24]

376.83 ± 31.961

527.17 ± 88.666

        

Ming-ying Gai[25]

322.26 ± 148.15

358.34 ± 148.07

42.75 ± 40.45

74.25 ± 77.06

359.29 ± 152.02

439.36 ± 191.48

    

Tullika Singh

202.25 ± 29.244

392.20 ± 24.314

66.80 ± 11.852

112.25 ± 18.523

270.05 ± 30.883

510.45 ± 30.342

    

A. V. Chandak

308.8 ± 43.6

349.18 ± 42.17

79.0 ± 14.18

128.57 ± 23.72

      

Leila Sekhavat

  

28.0 ± 5.5

37.1 ± 9.0

    

0.1 ± 0.6

2.5 ± 0.8

Irene Ray

499.75 ± 111.20

690.85 ± 198.41

59.93 ± 12.5

110.06 ± 13.47

559.68 ± 113.80

800.91 ± 200.26

  

0.26 ± 0.22

0.99 ± 0.48

S.J. Dhivya Lakshmi

347.17 ± 108.6

517.72 ± 150

        

Khing Rushulo

339.0 ± 18.4

377 ± 24.0

48.7 ± 9.1

58.4. ± 9.7

388.0 ± 22.8

432.4 ± 30.8

  

0.52 ± 0.2

0.84 ± 0.2

P. Malathi

375 ± 69

410 ± 79.9

52 ± 30

131 ± 42

    

1.34 ± 0.15

1.44 ± 0.88

Samir Abd Allah Ali

386.55 ± 104.98

507.76 ± 152.14

114.73 ± 53.82

139.67 ± 73.35

501.28 ± 119.2

647.43 ± 178.77

0/100

1/100

0.73 ± 0.58

1.35 ± 0.56

Ayman A. Soliman

286.82 ± 47.42

406.74 ± 60.56

143.46 ± 23.61

203.36 ± 30.30

430.28 ± 71.03

610.10 ± 90.87

    

Noshina Shabir

500.62 ± 111.20

696.85 ± 196.32

60.96 ± 13.4

112.02 ± 13.46

561.64 ± 113.79

801.71 ± 200.12

    
  1. Values are given as mean ± standard deviation
  2. a blood loss from placental delivery to the end of CS (mL)
  3. b blood loss from end of CS to 2 h postpartum (mL)
  4. c blood loss from placental delivery to 2 h postpartum (mL)
  5. * blood loss from end of CS to 6 h postpartum (mL)
  6. # blood loss from placental delivery to 6 h postpartum (mL)
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BMC Pregnancy and Childbirth

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