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Table 2 Clinical characteristics of HBV-infected mothers at delivery

From: Effect of prophylactic antiviral intervention on T cell immunity in hepatitis B virus-infected pregnant women

 

Intervention group (n = 34)

Non-intervention group (n = 15)

P value

Age-yr

27.50 (26.00,30.00)

26.00 (24.00,32.00)

0.535

Gravidity

1.00 (1.00,2.00)

1.00 (1.00,2.00)

0.774

Delivery by means of cesarean section — no. (%)

11 (32.35%)

5(33.33%)

 > 0.999

Gestational age—wk

39.50 (39.00,40.00)

39.00 (38.00,39.00)

0.080

Duration of antiviral intervention—dy

89.50 (72.00, 100.0)

-

 

LDT treatment-no.(%)

24(70.59%)

-

 

TDF treatment-no.(%)

10(29.41%)

-

 

ALT(U/L)

16.00(12.50,20.00)

20.00(15.00,35.00)

0.113

AST(U/L)

21.00(17.00,27.00)

24.00(16.00,30.00)

0.624

HBsAg(IU/ml)

15,549(3644,32,316)

8456(2229,52,000)

0.862

HBeAg(COI)

1320(809.6,1548)

1448(1174,1767)

0.219

HBV DNA(log10 IU/ml)

3.38 (2.38,4.37)

7.70 (6.58,8.57)

 < 0.001

  1. Data are shown as Median (IQR, interquartile range)
  2. Abbreviations: ALT Alanine aminotransferase, AST Aspartate aminotransferase, COI cut off index, IQR Interquartile range, LDT Telbivudine, TDF Tenofovir disoproxil fumarate, HBsAg Hepatitis B surface antigen, HBeAg Hepatitis B E antigen, HBV hepatitis B virus, DNA Deoxyribonucleic acid