Fig. 5

Prophylactic antiviral intervention in late pregnancy had no significant effect on maternal T cells after delivery (A) Comparison of the difference in Treg frequency in intervention mothers (n = 20) with non-intervention mothers (n = 6) at postpartum 6–8 weeks or 15–18 weeks; (B) Treg frequency changes before, during and after withdrawal of antiviral drugs in a chronic HBV infected mother during the first and second pregnancy; (C-D) Percentages of cytokine-producing CD4 + T cells in intervention (n = 20) or non-intervention (n = 6) mothers at postpartum 6–8 or 15–18 weeks, respectively and the data represent Th1:Th2-cytokine ratio (IFN-γ:IL-10) in CD4 + T cells. (E–F) Percentages of cytokine-producing CD8 + T cells in intervention (n = 20) or non-intervention (n = 6) mothers at postpartum 6–8 or 15–18 weeks, respectively and the data represent Th1:Th2-cytokine ratio ((IFN-γ:IL-10) in CD8 + T cells. The data represent the median with 95% CI. *P < 0.05