Skip to main content

Table 2 Neonatal outcomes among offspring of mothers with a documented penicillin allergy versus those without a documented penicillin allergy

From: Antibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes

Outcome

Documented maternal penicillin allergy

(n = 1170)

Absence of documented maternal penicillin allergy

(n = 10164)

p-value

OR (95% CI)

aOR (95% CI)c

Blood drawn for lab testa

243 (20.8)

1758 (17.3)

< 0.01

1.25 (1.08–1.46)

1.23 (1.06–1.43)

 Complete blood count

241 (20.6)

40 (3.4)

1751 (17.2)

331 (3.3)

   

 C-reactive protein

209 (17.9)

1447 (14.2)

   

 Blood culture

     

Positive blood cultureb

3 (3.3)

16 (2.5)

0.64

1.71 (0.56–5.21)

NAd

Receipt of postnatal antibiotics

80 (6.8)

563 (5.5)

0.07

1.25 (0.98–1.59)

1.20 (0.94–1.53)

NICU admission

101 (8.6)

775 (7.6)

0.22

1.14 (0.92–1.42)

1.11 (0.89–1.38)

Birth hospitalization length of stay, hours

56.6 (50.6–66.6)

55.6 (50.0-64.4)

< 0.01

NA

NA

  1. Data presented as n (%), median (interquartile range), p-values, and odds ratio (95% confidence intervals)
  2. a A single blood draw may have encompassed a single or multiple laboratory tests
  3. b Frequencies calculated as the number of positive blood cultures divided by total number of blood cultures performed
  4. c Adjusted for maternal age at delivery, maternal race and ethnicity, and intrapartum cesarean delivery
  5. d Modeling not performed due to low frequencies of events