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Table 8 Performance metrics (95% confidence interval) balancing sensitivity and specificity

From: Development and internal validation of a non-invasive clinical tool to predict sufficient omega-3 levels in early pregnancy

Model Predictors*

Estimated n-3 intake (mg/week)

Youden’s Index

Concordance Probability

Closest to (0,1) Corner

Index of Union

Dietary and supplementary intake of total n-3

767.8

0.394

(0.390–0.398)

0.462

(0.459–0.465)

0.546

(0.542–0.550)

0.303

(0.298–0.309)

Dietary and supplementary intake of total n-3 with 1.0% ALA conversion

797.0

0.380

(0.376–0.385)

0.453

(0.450–0.457)

0.489

(0.486–0.493)

0.298

(0.293–0.304)

Dietary and supplementary intake of total n-3 LCPUFA

630.1

0.358

(0.353–0.362)

0.422

(0.419–0.425)

0.534

(0.530–0.537)

0.386

(0.380–0.393)

Dietary and supplementary intake of total n-3 with 1.0% ALA conversion

670.9

0.329

(0.325–0.333)

0.405

(0.402–0.409)

0.482

(0.478–0.486)

0.369

(0.362–0.376)

Dietary and supplementary intake of total n-3 LCPUFA

558.1

0.361

(0.312–0.320)

0.392

(0.388–0.395)

0.563

(0.559–0.567)

0.395

(0.387–0.403)

  1. *All models were adjusted for maternal age, BMI, IRSAD and n-3 additions. Dietary intake refers to n-3 from food items whilst supplementary intake refers to n-3 from supplement use
  2. Mg = milligrams; n-3 = omega-3; LCPUFA = long-chain polyunsaturated fatty acids; ALA = alpha-linolenic acid