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Fig. 2 | BMC Pregnancy and Childbirth

Fig. 2

From: Altered local RAS in the liver increased the risk of NAFLD in male mouse offspring produced by in vitro fertilization

Fig. 2

Effect of IVF-ET on glucose and lipid metabolism of male offspring. A: Glucose tolerance test in 4-week-old chow-fed male offspring (nNC−chow=11, nIVF−chow=12). B: Fast glucose of chow and HFD treatment male offspring at 4,10,16 weeks (nNC−chow=13, nIVF−chow=12, nNC−HFD=13, nNC−HFD=13). C: Fast insulin of chow and HFD treatment male offspring at 4,10,16 weeks (nNC−chow=10, nIVF−chow=11, nNC−HFD=11, nNC−HFD=11). D: HOMA-IR of chow and HFD treatment male offspring at 4,10,16 weeks (nNC−chow=10, nIVF−chow=11, nNC−HFD=11, nNC−HFD=11). E: Lipid profile of chow and HFD treatment male offspring at 10,16 weeks (Left:TC, nNC−chow=11, nIVF−chow=11, nNC−HFD=12, nNC−HFD=12; Middle:TG, nNC−chow=12, nIVF−chow=11, nNC−HFD=12, nNC−HFD=11; Right:LDL, nNC−chow=11, nIVF−chow=12, nNC−HFD=12, nNC−HFD=11). *Indicates a significant difference (P < 0.05) between NC-Chow and IVF-Chow; #denotes NC-HFD vs. IVF-HFD (P < 0.05); ‘ns’ indicates a increased tend in IVF-Chow (0.05 < P < 0.1)

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