The role of routine first-trimester ultrasound screening for central nervous system abnormalities: a longitudinal single-center study using an unselected cohort with 3-year experience

Table 1 Baseline characteristics of the 38,586 pregnancies and 141 cases with CNS abnormalities

Characteristic		Fetuses with normal CNS	Cases with CNS abnormalities	P
Maternal age, years	Range	17–51	24–44	0.242
Maternal age, years	Average (SD)	31.5 (4.0)	31.9 (3.9)	0.242
Maternal height, cm	Range	140–186	150–178	0.918
Maternal height, cm	Average (SD)	162.8(5.0)	162.8(5.3)	0.918
Maternal weight, kg	Range	35.0-99.5	43.5–97.0	0.498
Maternal weight, kg	Average (SD)	59.0 (9.3)	58.4 (9.9)	0.498
Body-mass index, kg/m²	Range	13.0–40.0	16.9–37.5	0.443
Body-mass index, kg/m²	Average (SD)	22.2 (3.3)	22.0 (3.5)	0.443
Fetal CRL, mm		63.8 (7.2)	61.3 (8.4)	< 0.001
Fetal NT, mm		1.4 (0.5)	1.7 (1.4)	0.035

*Maternal baseline characteristics were measured during 11–13^+ 6 weeks’ gestation. (SD: standard deviation; CRL: crown-rump length; NT: nuchal translucency )

ISSN: 1471-2393