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Table 3 Neonatal outcomes of women with chorioamnionitis by infertility treatment

From: Association of chorioamnionitis with infertility treatment and subsequent neonatal outcomes in the US: a population-based cohort study

Characteristic

Women diagnosed with CAM

Natural conception

Infertility treatment

P- value

Population

174,254 (100.0)

169,668 (97.4)

4,586 (2.6)

 

Birth weight (mean) (g)

3,344 ± 631

3,344 ± 629

3,326 ± 693

 < .001

Birth weight

   

 < .001

  < 1500 g

4,349 (2.5)

4,183 (2.5)

166 (3.6)

 

 1500–2500 g

6,335 (3.6)

6,184 (3.6)

151 (3.3)

 

  ≥ 2500 g

163,370 (93.8)

159,110 (93.8)

4,260 (92.9)

 

 Unknown

200 (0.1)

191 (0.1)

9 (0.2)

 

Gestational age (mean) (weeks)

38.8 ± 2.8

38.8 ± 2.7

38.6 ± 3.2

 

Gestational age

   

 < .001

  < 28

3,226 (1.9)

3,105 (1.8)

131 (2.9)

 

 28–31+6

2,140 (1.2)

2,068 (1.2)

72 (1.6)

 

 32–36+6

7,277 (4.2)

7,070 (4.2)

207 (4.5)

 

  ≥ 37

161,547 (92.7)

157,372 (92.8)

4,175 (91.0)

 

 Unknown

54 (0.0)

53 (0.0)

1 (0.0)

 

Apgar 5 min

   

 < .001

 

8.5 ± 1.2

8.5 ± 1.2

8.5 ± 1.3

 

NICU admission

   

 < .001

 

52,348 (30.0)

50,856 (30.0)

1,492 (32.5)

 

Assisted ventilation

   

 < .001

 

18,960 (10.9)

18,351 (10.8)

609 (13.3)

 

Assisted ventilation > 6 h

   

 < .001

 

6046 (3.5)

5828 (3.4)

218 (4.8)

 

Use of surfactant

   

 < .001

 

1,880 (1.1)

1,800 (1.1)

80 (1.7)

 

Use of antibiotics

   

 < .001

 

42,180 (24.2)

40,760 (24.0)

1,420 (31.0)

 

Seizure

   

0.154

 

215 (0.1)

206 (0.1)

9 (0.2)

 
  1. aThe mother-infant pairs without neonatal outcomes records were excluded N = 6690 (0.1%). And for gestational age and birth weight, the missing value were retained