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Table 3 Crude and adjusted odds ratio obtained through logistic regression analysis for the association between Acute Respiratory Distress (ARD) during pregnancy and fetal deaths. Bahia, Brazil, Jan 2019—Jun 2021 a

From: Fetal death as an outcome of acute respiratory distress in pregnancy, during the COVID-19 pandemic: a population-based cohort study in Bahia, Brazil

Covariates

Crude Odds Ratiob

CI 95%

Fully adjusted Odds Ratio c

CI 95%

ARD during pregnancy

 No

1

-

1

-

 Yes

3.22

2.26;4.60

4.06

2.66;6.21

Age group (years)

  ≤ 19

1

-

1

-

 20 – 35

0.89

0.81;0.99

1.12

0.99;1.27

  ≥ 36

1.34

1.18;1.54

1.57

1.34;1.84

Education (in years)

 12 or more

1

-

1

-

 08 – 11

1.22

1.05;1.41

1.11

0.95;1.31

 4 – 7

2.02

1.72;2.37

1.72

1.45;2.05

 0 – 3

6.14

5.13;7.36

4.17

3.41;5.10

Type of pregnancy

 Single fetus

1

-

1

-

 Twin fetus or more

3.11

2.64;3.66

3.88

3.20;4.70

Fetus sex

 Female

1

-

1

-

 Male

1.18

1.09;1.27

1.19

1.09;1.31

Type of delivery

 Vaginal

1

-

1

-

 Cesarean

0.44

0.39;0.47

0.43

0.38;0.47

HDI on the municipality of residence

 High or Very High (≥ 0.700)

1

-

1

-

 Medium (0.600—0.699)

1.16

1.05;1.28

0.99

0.89;1.11

 Low or Very Low (≤ 0.599)

1.25

1.13;1.39

0.97

0.86;1.10

  1. Source: Live birth information system (SINASC); Mortality information system (SIM); Epidemiological Surveillance System of Acute Respiratory Distress (SIVEP); Brazilian Institute of Geography and Statistics (IBGE)
  2. HDI Human Development Index
  3. aThe exposed group (ARD during pregnancy = Yes) is composed of women who had ARD in pregnancy during the COVID-19 pandemic period (Jan 2020 to Jun 2021). The non-exposed group (ARD during pregnancy = No) comprised women who had a pregnancy before the onset of the COVID-19 pandemic (Jan to Dec 2019) and did not have ARD during pregnancy. These groups differ not only because of ARD during pregnancy but also because of the environmental changes resulting from the COVID-19 pandemic
  4. bBivariate analysis
  5. cAdjusted for ARD during pregnancy, age group, education, fetus sex, type of pregnancy, type of delivery, and HDI of the municipality of residence of pregnant women