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Table 4 Effect of interpregnancy interval (IPI) on maternal adverse events

From: Association between interpregnancy interval and maternal and neonatal adverse outcomes in women with a cesarean delivery: a population-based study

Outcome

Interpregnancy interval

 ≤ 11 month

12 ~ 17 month

18 ~ 23 month

24 ~ 35 month

36 ~ 59 month

 ≥ 60 month

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

OR (95% CI)

P

OR (95% CI)

P

OR (95% CI)

P

Maternal adverse events

 Total population

1.01 (0.81–1.25)

0.919

1.01 (0.89–1.15)

0.827

1.00 [Ref]

0.95 (0.86–1.05)

0.347

0.92 (0.84–1.02)

0.102

0.91 (0.82–0.99)

0.052

 Age group

   < 35

1.07 (0.86–1.34)

0.544

1.03 (0.90–1.18)

0.680

1.00 [Ref]

0.91 (0.82–1.02)

0.115

0.91 (0.82–1.02)

0.108

0.85 (0.76–0.95)

0.004

   ≥ 35

0.52 (0.21–1.29)

0.161

0.90 (0.64–1.27)

0.549

1.00 [Ref]

1.11 (0.89–1.39)

0.361

0.95 (0.76–1.18)

0.620

1.03 (0.83–1.28)

0.771

 Previous preterm births group

  No

1.05 (0.83–1.32)

0.694

0.99 (0.87–1.14)

0.955

1.00 [Ref]

0.97 (0.87–1.08)

0.577

0.94 (0.84–1.04)

0.219

0.92 (0.83–1.03)

0.137

  Yes

0.77 (0.43–1.37)

0.371

1.11 (0.77–1.60)

0.574

1.00 [Ref]

0.80 (0.59–1.10)

0.179

0.78 (0.57–1.06)

0.116

0.76 (0.56–1.03)

0.080

Maternal transfusion

 Total population

0.90 (0.68–1.18)

0.435

0.91 (0.78–1.07)

0.265

1.00 [Ref]

0.92 (0.82–1.04)

0.182

0.88 (0.78–0.99)

0.033

0.86 (0.76–0.97)

0.015

 Age group

   < 35

0.99 (0.75–1.30)

0.923

0.97 (0.81–1.14)

0.681

1.00 [Ref]

0.90 (0.79–1.03)

0.123

0.90 (0.79–1.02)

0.110

0.82 (0.72–0.94)

0.004

   ≥ 35

0.31 (0.08–1.25)

0.100

0.66 (0.42–1.03)

0.069

1.00 [Ref]

0.98 (0.75–1.27)

0.868

0.77 (0.59–1.01)

0.057

0.87 (0.67–1.12)

0.285

 Previous preterm births group

  No

0.90 (0.67–1.21)

0.482

0.90 (0.76–1.06)

0.211

1.00 [Ref]

0.94 (0.83–1.07)

0.332

0.88 (0.77–0.99)

0.036

0.87 (0.77–0.99)

0.032

  Yes

0.86 (0.41–1.80)

0.688

1.03 (0.64–1.68)

0.894

1.00 [Ref]

0.73 (0.48–1.11)

0.143

0.89 (0.60–1.32)

0.563

0.75 (0.50–1.12)

0.154

Ruptured uterus

 Total population

1.47 (0.91–2.38)

0.116

1.27 (0.95–1.70)

0.107

1.00 [Ref]

0.86 (0.68–1.09)

0.212

0.79 (0.63–1.01)

0.059

0.64 (0.50–0.83)

 < 0.001

 Age group

   < 35

1.52 (0.92–2.50)

0.099

1.26 (0.93–1.72)

0.140

1.00 [Ref]

0.79 (0.61–1.03)

0.083

0.77 (0.59–0.99)

0.046

0.59 (0.45–0.78)

 < 0.001

   ≥ 35

0.95 (0.13–7.21)

0.961

1.28 (0.57–2.92)

0.549

1.00 [Ref]

1.18 (0.66–2.11)

0.573

0.91 (0.50–1.64)

0.749

0.84 (0.46–1.51)

0.557

 Previous preterm births group

   No

1.54 (0.91–2.58)

0.105

1.27 (0.93–1.73)

0.127

1.00 [Ref]

0.84 (0.65–1.08)

0.168

0.80 (0.62–1.03)

0.087

0.65 (0.50–0.86)

0.002

   Yes

1.09 (0.30–3.99)

0.900

1.24 (0.52–2.94)

0.626

1.00 [Ref]

1.05 (0.51–2.17)

0.898

0.73 (0.34–1.56)

0.415

0.58 (0.26–1.29)

0.181

Unplanned hysterectomy

 Total population

0.79 (0.36–1.74)

0.562

0.89 (0.58–1.37)

0.604

1.00 [Ref]

0.96 (0.70–1.30)

0.769

1.03 (0.76–1.38)

0.861

0.92 (0.68–1.24)

0.586

 Age group

   < 35

0.71 (0.30–1.66)

0.424

0.77 (0.47–1.27)

0.308

1.00 [Ref]

0.91 (0.63–1.30)

0.590

1.02 (0.72–1.45)

0.914

0.99 (0.70–1.42)

0.977

   ≥ 35

0.83 (0.11–6.26)

0.853

1.17 (0.52–2.63)

0.706

1.00 [Ref]

1.16 (0.66–2.04)

0.617

1.17 (0.67–2.04)

0.578

1.18 (0.69–2.04)

0.543

 Previous preterm births group

   No

0.66 (0.26–1.64)

0.369

0.92 (0.59–1.42)

0.693

1.00 [Ref]

0.92 (0.67–1.27)

0.624

1.03 (0.76–1.39)

0.863

0.90 (0.66–1.22)

0.485

   Yes

1.66 (0.29–9.51)

0.568

0.68 (0.12–3.77)

0.662

1.00 [Ref]

1.41 (0.45–4.44)

0.560

1.01 (0.31–3.32)

0.982

1.24 (0.40–3.88)

0.714

Admission to ICU

 Total population

0.91 (0.57–1.45)

0.687

1.08 (0.82–1.42)

0.593

1.00 [Ref]

1.02 (0.82–1.27)

0.828

1.13 (0.92–1.39)

0.257

1.16 (0.94–1.42)

0.157

 Age group

   < 35

0.89 (0.54–1.46)

0.640

1.07 (0.79–1.45)

0.645

1.00 [Ref]

0.98 (0.77–1.25)

0.870

1.11 (0.88–1.40)

0.381

1.10 (0.87–1.39)

0.426

   ≥ 35

0.80 (0.19–3.44)

0.769

0.98 (0.49–1.96)

0.948

1.00 [Ref]

1.25 (0.78–2.01)

0.350

1.30 (0.82–2.05)

0.264

1.56 (1.01–2.41)

0.047

 Previous preterm births group

   No

1.05 (0.63–1.73)

0.862

1.02 (0.75–1.39)

0.911

1.00 [Ref]

1.04 (0.82–1.31)

0.768

1.19 (0.95–1.49)

0.130

1.21 (0.97–1.51)

0.088

   Yes

0.41 (0.12–1.43)

0.164

1.27 (0.67–2.41)

0.466

1.00 [Ref]

0.97 (0.55–1.70)

0.904

0.79 (0.45–1.39)

0.409

0.87 (0.50–1.52)

0.633

  1. OR odds ratio, CI confidence interval, Ref reference, ICU intensive care unit; OR shows the results of multivariate logistic regression analysis after adjusting for age (unadjusted in age group analysis), race, education level, marital status, weight gain, smoking before pregnancy, smoking during pregnancy, prenatal care, pre-pregnancy BMI, pre-pregnancy diabetes, gestational diabetes, pre-pregnancy hypertension, gestation hypertension, eclampsia, assisted reproductive treatment, gestational age, clinical chorioamnionitis or maternal fever during labor, and previous preterm birth (unadjusted in previous preterm births group analysis)
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BMC Pregnancy and Childbirth

ISSN: 1471-2393

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