Association between interpregnancy interval and maternal and neonatal adverse outcomes in women with a cesarean delivery: a population-based study

Table 3 Association between interpregnancy interval (IPI) and risk of repeat cesarean delivery in women who underwent a trial of labor after cesarean (TOLAC)

Variables	Women with TOLAC (n)	Repeat cesarean delivery (%)	Univariate analysis		Multivariate analysis
Variables	Women with TOLAC (n)	Repeat cesarean delivery (%)	OR (95%CI)	P	OR (95%CI)	P
	133,970	46,042 (34.37%)
Interpregnancy interval
18–23 month	18,564	5765 (31.05%)	Ref		Ref
≤ 11 month	1593	582 (36.53%)	1.28 (1.15–1.42)	< 0.001	1.21 (1.08–1.35)	0.001
12–17 month	8506	2987 (35.12%)	1.20 (1.14–1.27)	< 0.001	1.15 (1.08–1.21)	< 0.001
24–35 month	35,344	11,018 (31.17%)	1.01 (0.97–1.04)	0.777	0.99 (0.95–1.03)	0.483
36–59 month	34,923	11,881 (34.02%)	1.14 (1.10–1.19)	< 0.001	1.05 (1.01–1.10)	0.011
≥ 60 month	35,040	13,809 (39.41%)	1.44 (1.39–1.50)	< 0.001	1.16 (1.11–1.21)	< 0.001

OR odds ratio, CI confidence interval, Ref reference
Multivariate logistic regression analysis adjusted for age, race, education level, marital status, weight gain, smoking before pregnancy, smoking during pregnancy, prenatal care, pre-pregnancy BMI, pre-pregnancy diabetes, gestational diabetes, pre-pregnancy hypertension, gestation hypertension, eclampsia, assisted reproductive treatment, gestational age, clinical chorioamnionitis or maternal fever during labor, and previous preterm birth

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