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Table 2 Incidence proportions of adverse infant outcomes by study cohort

From: Adverse infant outcomes following low-risk pregnancies in England: a retrospective cohort study

 

AP infants cohort N = 185 119

AP24 + infants cohort N = 183 869

LR infants cohort N = 121 871

n

Incidence/10 000 (95% CI)

n

Incidence/10 000 (95% CI)

n

Incidence/10 000 (95% CI)

Assessed during period as stated

Neonatal death (birth–day 28)

33

1.8 (1.3–2.4)

33

1.8 (1.3–2.4)

17

1.4 (0.9–2.1)

Infant death (days 29–90)

45

2.4 (1.8–3.2)

42

2.3 (1.7–3.0)

22

1.8 (1.2–2.6)

Early-onset sepsis (birth–day 7)

2 306

124.6 (119.5–129.8)

2 288

124.4 (119.3–129.7)

1 329

109.0 (103.2–115.2)

Late-onset sepsis (days 8–90)

818

44.2 (41.2–47.3)

809

44.0 (41.0–47.2)

501

41.1 (37.6–44.9)

Assessed from birth to day 90

Very low/low birth weight

8 380

452.7 (442.9–462.6)

8 334

453.3 (443.5–463.2)

4 882

400.6 (389.3–412.1)

Macrosomia

19 718

1 065.2 (1 050.8–1 079.7)

19 543

1 062.9 (1 048.4–1 077.4)

13 234

1 085.9 (1 068.1–1 103.9)

Small for gestational age

918

49.6 (46.4–53.0)

915

49.8 (46.5–53.2)

565

46.4 (42.6–50.4)

Large for gestational age

1 910

103.2 (98.6–107.9)

1 896

103.1 (98.5–107.9)

1 185

97.2 (91.8–102.9)

Assessed from start of pregnancy to day 90

Minor congenital anomalies

15 447

834.4 (821.8–847.3)

15 346

834.6 (821.9–847.5)

9 757

800.6 (785.3–816.1)

Major congenital anomalies

5 519

298.1 (290.4–306.0)

5 476

297.8 (290.0–305.8)

3 296

270.4 (261.4–279.8)

  1. Incidence, incidence proportion per 10 000 live births; AP infants cohort, All Pregnancies infants cohort; AP24 + infants cohort, All Pregnancies with gestational age ≥ 24 weeks infants cohort; LR infants cohort, Low-Risk pregnancies infants cohort; N, number of linked infants included in the analysis in each cohort; n, number of linked infants in the specified category; CI, confidence interval
  2. If a particular outcome occurred several times for the same linked infant, it was only counted once for that linked infant. More than one linked infant can be included for the same mother