From: Adverse infant outcomes following low-risk pregnancies in England: a retrospective cohort study
AP infants cohort N = 185 119 | AP24 + infants cohort N = 183 869 | LR infants cohort N = 121 871 | ||||
---|---|---|---|---|---|---|
n | Incidence/10 000 (95% CI) | n | Incidence/10 000 (95% CI) | n | Incidence/10 000 (95% CI) | |
Assessed during period as stated | ||||||
Neonatal death (birth–day 28) | 33 | 1.8 (1.3–2.4) | 33 | 1.8 (1.3–2.4) | 17 | 1.4 (0.9–2.1) |
Infant death (days 29–90) | 45 | 2.4 (1.8–3.2) | 42 | 2.3 (1.7–3.0) | 22 | 1.8 (1.2–2.6) |
Early-onset sepsis (birth–day 7) | 2 306 | 124.6 (119.5–129.8) | 2 288 | 124.4 (119.3–129.7) | 1 329 | 109.0 (103.2–115.2) |
Late-onset sepsis (days 8–90) | 818 | 44.2 (41.2–47.3) | 809 | 44.0 (41.0–47.2) | 501 | 41.1 (37.6–44.9) |
Assessed from birth to day 90 | ||||||
Very low/low birth weight | 8 380 | 452.7 (442.9–462.6) | 8 334 | 453.3 (443.5–463.2) | 4 882 | 400.6 (389.3–412.1) |
Macrosomia | 19 718 | 1 065.2 (1 050.8–1 079.7) | 19 543 | 1 062.9 (1 048.4–1 077.4) | 13 234 | 1 085.9 (1 068.1–1 103.9) |
Small for gestational age | 918 | 49.6 (46.4–53.0) | 915 | 49.8 (46.5–53.2) | 565 | 46.4 (42.6–50.4) |
Large for gestational age | 1 910 | 103.2 (98.6–107.9) | 1 896 | 103.1 (98.5–107.9) | 1 185 | 97.2 (91.8–102.9) |
Assessed from start of pregnancy to day 90 | ||||||
Minor congenital anomalies | 15 447 | 834.4 (821.8–847.3) | 15 346 | 834.6 (821.9–847.5) | 9 757 | 800.6 (785.3–816.1) |
Major congenital anomalies | 5 519 | 298.1 (290.4–306.0) | 5 476 | 297.8 (290.0–305.8) | 3 296 | 270.4 (261.4–279.8) |