Longitudinal study of the relationship between number of prior miscarriages or stillbirths and changes in quality of life of pregnant women: the Japan Environment and Children’s Study (JECS)

Table 2 Results of linear mixed model analyses of PCS and MCS scores for pregnant women

Effect	Level	Period	Crude		Adjusted^a
	NMS		PCS	MCS	PCS	MCS
	NMS		β (95%CI)	β (95%CI)	β (95%CI)	β (95%CI)
Period		Early	reference	reference	reference	reference
Period		Mid/late	0.66 (0.60, 0.72)	3.05 (3.00, 3.11)	0.66 (0.40, 0.92)	2.20 (1.95, 2.45)
NMS	0	Early	45.13 (45.07, 45.18)	46.05 (45.99, 46.10)	reference	reference
	1	Early	− 0.51 (− 0.65, − 0.37)	− 0.06 (− 0.20, 0.08)	− 0.29 (− 0.42, − 0.15)	− 0.12 (− 0.25, 0.02)
	2	Early	− 0.78 (− 1.07, − 0.49)	− 0.10 (− 0.38, 0.18)	− 0.45 (− 0.73, − 0.18)	− 0.15 (− 0.42, 0.13)
	≥ 3	Early	− 1.42 (− 1.97, − 0.86)	− 0.16 (− 0.71, 0.40)	− 0.87 (− 1.39, − 0.35)	− 0.14 (− 0.66, 0.39)
NMS × Period	0 ×	Mid/late	reference	reference	reference	reference
	1 ×	Mid/late	0.19 (0.04, 0.35)	0.08 (− 0.06, 0.23)	0.22 (0.07, 0.37)	0.12 (− 0.03, 0.26)
	2 ×	Mid/late	0.17 (− 0.15, 0.49)	− 0.15 (− 0.45, 0.15)	0.21(− 0.01, 0.52)	− 0.08 (− 0.38, 0.21)
	≥ 3 ×	Mid/late	0.81 (0.21, 1.41)	− 0.06 (− 0.67, 0.55)	0.75 (0.18, 1.33)	− 0.01 (− 0.61, 0.59)

Boldface indicates significance at p values less than 0.05
NMS Number of miscarriages or stillbirths, PCS Physical Component Summary, MCS Mental Component Summary
^aAdjusted for age during pregnancy; pre-pregnancy BMI; parity; physical activity; history of depression, anxiety disorder, dysautonomia, or schizophrenia; history of any physical disease; marital status; employed during early pregnancy; highest educational level; annual household income; alcohol intake; smoking status; morning sickness; questionnaires administered in early pregnancy; questionnaires administered in mid/late pregnancy

ISSN: 1471-2393