Fig. 2

Monocyte response to TLR7 stimulation. A Proportions of monocyte subsets in pregnant (red) and non-pregnant women (blue) with and without Gardiquimod stimulation (TLR7 agonist). B Heatmap representation of the differences in proportions of monocyte subsets from pregnant (red symbols) and non-pregnant (blue symbols) women following Gardiquimod stimulation. Asterisks indicate statistically significant differences between the indicated groups. C-F Frequencies of (C) classical monocytes (CD14^hiCD16⁻), (D) intermediate monocytes (CD14^hiCD16⁺), (E) non-classical monocytes (CD14^loCD16⁺), (F) CD14^loCD16⁻ monocytes in pregnant (red) and non-pregnant (blue) women following Gardiquimod stimulation (solid circles) or control (open circles). *p < 0.05; **p < 0.01. ( +) Stimulated; (-) Control