Skip to main content

Table 2 Odds ratio (95% confidence interval) of GDM according to folate intake

From: Joint effect of maternal pre-pregnancy body mass index and folic acid supplements on gestational diabetes mellitus risk: a prospective cohort study

 

GDM/pregnancy

Crude OR

Adjusted OR

Food folate(ug/day)

   

Q1(28–130)

116/524

1.00(ref.)

1.00(ref.)

Q2(131–206)

84/525

1.03(0.74–1.45)

1.02(0.72–1.44)

Q3(207–308)

88/523

1.16(0.83–1.62)

1.08(0.77–1.52)

Q4(308–1572)

84/523

0.94(0.66–1.33)

0.86(0.60–1.23)

P trend

 

0.846

0.980

Supplemental folate(ug/day)

   

< 400

35/186

1.00(ref.)

1.00(ref.)

≥ 400

337/1909

0.93(0.63–1.36)

0.86(0.58–1.30)

P

 

0.692

0.483

Total folate(ug/day)

   

Q1(38–602)

102/524

1.00(ref.)

1.00(ref.)

Q2(603–833)

80/527

0.80(0.58–1.12)

0.78(0.56–1.10)

Q3(834–1001)

95/522

0.92(0.68–1.26)

0.82(0.58–1.17)

Q4(1001–2296)

95/522

1.01(0.73–1.39)

0.84(0.57–1.24)

P trend

 

0.762

0.919

Total folate(ug/day)

   

< 400

13/78

1.00(ref.)

1.00(ref.)

≥ 400

359/2017

0.84(0.44–1.60)

1.25(0.64–2.43)

P

 

0.595

0.518

  1. Q, quartile. Adjusted OR: adjusted for age, pre-pregnancy BMI, education level, monthly income, passive smoking, drinking, family history of diabetes mellitus, fertilization way, history of GDM, the use of vitamin B12 supplement