Table 1 Demographic and maternal characteristics of participants by hsCRP tertiles
From: Serum hsCRP in early pregnancy and preterm delivery in twin gestations: a prospective cohort study
N | Tertile 1 (N, %) | Tertile 2 (N, %) | Tertile 3 (N, %) | P | |
|---|---|---|---|---|---|
N | 618 | 205(33.2) | 209(33.8) | 204(33.0) | |
hsCRP in early pregnancy(mg/L) | 618 | 0.47(0.42,0.53) | 1.99(1.91,2.06) | 6.13(5.69,6.61) | |
Maternal age(year) | 618 | 32.61(32.04,33.19) | 33.28(32.80,33.77) | 33.67(33.12,34.23)ac | 0.011 |
Education level | < 0.001 | ||||
Middle school or less | 64 | 12(5.9) | 18(8.6) | 34(16.7)ac,bc | |
High school | 348 | 107(52.2) | 114(54.6) | 127(62.2) | |
Postgraduate or above | 206 | 86(41.9) | 77(36.8) | 43(21.1) | |
Couple income per year (10,000yuan) | 0.031 | ||||
< 12 | 156 | 43(21.0) | 47(22.5) | 66(32.3) | |
12 ~ | 115 | 44(21.5) | 35(16.7) | 36(17.7) | |
20 ~ | 148 | 48(23.4) | 48(23.0) | 52(25.5) | |
30 ~ | 199 | 70(34.1) | 79(37.8) | 50(24.5) | |
Prepregnant BMI (kg/m2) | < 0.001 | ||||
< 18.5 | 39 | 25(12.2) | 10(4.8) | 4(2.0)ab,ac,bc | |
18.5 ~ | 422 | 156(76.1) | 157(75.1) | 109(53.4) | |
24 ~ | 157 | 24(11.7) | 42(20.1) | 91(44.6) | |
Parity | 0.573 | ||||
0 | 527 | 179(87.3) | 175(83.7) | 173(84.8) | |
1 ~ | 91 | 26(12.7) | 34(16.3) | 31(15.2) | |
Active or passive smoke | 0.733 | ||||
No | 501 | 165(80.5) | 173(82.8) | 163(79.9) | |
Yes | 117 | 40(19.5) | 36(17.2) | 41(20.1) | |
Alcohol | 0.367 | ||||
No | 552 | 178(86.8) | 189(90.4) | 185(90.7) | |
Yes | 66 | 27(13.2) | 20(9.6) | 19(9.3) | |
Anti-inflammatory drugs use | 0.405 | ||||
No | 455 | 145(70.7) | 160(76.6) | 150(73.5) | |
Yes | 163 | 60(29.3) | 49(23.4) | 54(26.5) | |
Progestogens use | 0.004 | ||||
No | 142 | 60(29.4) | 50(24.0) | 32(15.8)ac | |
Yes | 473 | 144(70.6) | 158(76.0) | 171(84.2) | |
Type of conception | 0.008 | ||||
Spontaneous | 180 | 72(35.3) | 64(30.6) | 44(21.6)ac | |
Assisted reproductive technology | 437 | 132(64.7) | 145(69.4) | 160(78.4) | |
Type of chorionic membrane | 0.347 | ||||
Dichorion | 455 | 144(70.6) | 155(74.5) | 156(76.9) | |
Monochorion | 160 | 60(29.4) | 53(25.5) | 47(23.1) | |
Gestational weeks at blood drawing | 618 | 8.56(8.31,8.81) | 8.94(8.69,9.19) | 9.16(8.89,9.43)ac | 0.005 |
Threatened premature labor | 0.999 | ||||
No | 476 | 158(77.1) | 161(77.0) | 157(77.0) | |
Yes | 142 | 47(22.9) | 48(23.0) | 47(23.0) | |
Premature rupture of membrane | 0.342 | ||||
No | 506 | 165(80.9) | 177(85.9) | 164(81.6) | |
Yes | 105 | 39(19.1) | 29(14.1) | 37(18.4) | |
Fetal loss | 0.367 | ||||
No | 526 | 178(86.8) | 172(82.3) | 176(86.3) | |
Yes | 92 | 27(13.2) | 37(17.7) | 28(13.7) |