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Table 5 Comparison between groups regarding pregnancy outcome

From: Maternal Interleukin-17 and disease activity influence pregnancy outcomes in women with psoriatic arthritis and ankylosing spondylitis

 

Control

(N = 30)

PsA

(N = 26)

AS

(N==22)

Adjusted OR

(95% CI)

N (%)

N (%)

N (%)

a OR * 1

a OR * 2

Gestational age at delivery:

Preterm < 37 weeks N (%)

3 (10)

7 (26.9)

4 (18.2)

1.80(0.79–4.17)

1.48 (0.65–3.38)

Term ≥ 37 weeks N (%)

27 (90)

18 (69.2)

16 (72.7)

1.32 (0.57–1.76)

1.01 (1.48–2.36)

Obstetric complications:

Pre-eclampsia

 Early onset (<  34 wk.) N (%)

0

3 (11.5)

1 (4.5)

N/A

N/A

 Late onset (≥ 34 wk.) N (%)

3 (10)

5 (19.2)

2 (9)

2.01 (0.81–2.35)

0.93 (0.46–1.42)

Gestational diabetes N (%)

2 (6.6)

3 (11.5)

1 (4.5)

1.24 (0.51–1.63)

0.62 (0.35–2.21)

Oligohydramnios N (%)

3 (10)

7 (26.9)

4 (18.2)

3.15 (1.26–8.42)

2.14 (0.26–10.43)

APH N (%)

0

1 (3.8)

1 (4.5)

N/A

N/A

PPROM N (%)

1 (3.3)

3 (11.5)

2 (9)

1.34(0.73–2.49)

0.95 (0.35–1.62)

Complicated Delivery:

 Assisted vaginal

3 (10)

5 (19.2)

3 (13.6)

1.24 (0.51–1.63)

0.91 (0.52–1.71)

 Cesarean section

8 (26.7)

15 (57.7)

12 (54.5)

1.57 (1.41–2.68)

1.03 (0.73–1.31)

Neonatal outcome:

 SGA

1 (3)

1 (3.8)

2 (9)

1.52 (0.76–3.04)

7.04 (2.36–12.42)

 Apgar < 7 at 5 min.

2 (6.6)

4 (15.3)

4 (18.2)

1.28 (0.21–1.25)

1.62 (1.15–2.53)

 Neonatal death

1 (3)

2 (7.6)

1 (4.5)

1.21 (0.83–2.03)

1.13 (0.41–1.36)

  1. * Adjusted risk ratio computed using Poisson regression with robust standard errors for: Maternal age, Race (white), SES (high), BMI, Parity, and previous adverse pregnancy outcome (preeclampsia, preterm, Gestational Diabetes); a OR * 1 = Adjusted risk ratio of PsA group; a OR * 2 = Adjusted risk ratio of AS group; SGA = small for gestational age