From: Pregnancy outcomes in women with pulmonary hypertension: a retrospective study in China
Covariates | PH groups | P-value | ||||
---|---|---|---|---|---|---|
Total (n = 154) | iPAH (n = 6) | CHD-PAH (n = 41) | oPAH (n = 45) | LHD-PH (n = 62) | ||
Maternal outcomes | ||||||
Mode of delivery, n (%) | 0.006 | |||||
Caesarean section | 108 (70.1) | 4 (66.7) | 31 (75.6) | 23 (51.1) | 50 (80.6) | |
Vaginal delivery | 29 (18.8) | 2 (33.3) | 3 (7.3) | 16 (35.6) | 8 (12.9) | |
Way of anaesthesia, n (%) | 0.005 | |||||
General anaesthesia | 52 (33.8) | 4 (66.7) | 11 (26.8) | 11 (24.4) | 26 (41.9) | |
Spinal anaesthesia | 56 (36.4) | 0 (0) | 20 (48.8) | 12 (26.7) | 24 (38.7) | |
Complications | ||||||
NYHA cardiac function III-IV | 42 (27.3) | 4 (66.7) | 10 (24.4) | 7 (15.6) | 21 (33.9) | 0.026 |
Admission to ICU, n (%) | 54 (35.1) | 5 (83.3) | 15 (36.6) | 11 (24.4) | 23 (37.1) | 0.032 |
Postpartum haemorrhage, n (%) | 16 (10.4) | 1 (16.7) | 3 (7.3) | 8 (17.8) | 4 (6.5) | 0.197 |
Uterine fatigue, n (%) | 26 (16.9) | 1 (16.7) | 5 (12.2) | 10 (22.2) | 10 (16.1) | 0.642 |
Heart failure, n (%) | 23 (14.9) | 4 (66.7) | 1 (2.4) | 6 (13.3) | 12 (19.4) | < 0.001 |
MODS, n (%) | 8 (5.2) | 3 (50) | 1 (2.4) | 2 (4.4) | 2 (3.2) | 0.003 |
Cardiac arrest, n (%) | 1 (0.6) | 0 (0) | 0 (0) | 1 (2.2) | 0 (0) | 0.607 |
Maternal death, n (%) | 5 (3.2) | 3 (50) | 1 (2.4) | 0 (0) | 1 (1.6) | < 0.001 |
Foetal outcome | ||||||
Premature infants (< 37 weeks), n (%) | 66 (42.9) | 4 (66.7) | 13 (31.7) | 17 (37.8) | 32 (51.6) | 0.122 |
(34 ~ 37 weeks), n (%) | 30 (19.5) | 2 (33.3) | 4 (9.8) | 7 (15.6) | 17 (27.4) | 0.088 |
(< 34 weeks), n (%) | 36 (23.4) | 2 (33.3) | 9 (22) | 10 (22.2) | 15 (24.2) | 0.897 |
Birth weight of the newborn, mean ± SD | 2334.9 ± 814.6 | 2124.0 ± 837.4 | 2341.3 ± 799.3 | 2522.6 ± 974.0 | 2243.8 ± 718.8 | 0.374 |
LBW, n (%) | 44 (28.6) | 3 (50) | 8 (19.5) | 7 (15.6) | 26 (41.9) | 0.004 |
VLBW, n (%) | 20 (13.0) | 0 (0) | 7 (17.1) | 3 (6.7) | 10 (16.1) | 0.367 |
ELBW, n (%) | 5 (3.2) | 1 (16.7) | 1 (2.4) | 3 (6.7) | 0 (0) | 0.031 |
SGA, n (%) | 94 (61.0) | 4 (66.7) | 25 (61) | 17 (37.8) | 48 (77.4) | < 0.001 |
Therapeutic abortion | 15 (9.7) | 0 (0) | 7 (17.1) | 5 (11.1) | 3 (4.8) | 0.204 |
Intrauterine death, n (%) | 7 (4.5) | 0 (0) | 1 (2.4) | 5 (11.1) | 1 (1.6) | 0.132 |
Missed abortion, n (%) | 1 (0.6) | 0 (0) | 0 (0) | 1 (2.2) | 0 (0) | 0.589 |
Neonatal death (< 1 week), n (%) | 3 (1.9) | 0 (0) | 1 (2.4) | 1 (2.2) | 1 (1.6) | 0.43 |