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Table 3 Maternal and foetal outcomes

From: Pregnancy outcomes in women with pulmonary hypertension: a retrospective study in China

Covariates

PH groups

P-value

Total (n = 154)

iPAH

(n = 6)

CHD-PAH

(n = 41)

oPAH

(n = 45)

LHD-PH

(n = 62)

Maternal outcomes

Mode of delivery, n (%)

     

0.006

 Caesarean section

108 (70.1)

4 (66.7)

31 (75.6)

23 (51.1)

50 (80.6)

 

 Vaginal delivery

29 (18.8)

2 (33.3)

3 (7.3)

16 (35.6)

8 (12.9)

 

Way of anaesthesia, n (%)

    

0.005

 General anaesthesia

52 (33.8)

4 (66.7)

11 (26.8)

11 (24.4)

26 (41.9)

 

 Spinal anaesthesia

56 (36.4)

0 (0)

20 (48.8)

12 (26.7)

24 (38.7)

 

Complications

 NYHA cardiac function III-IV

42 (27.3)

4 (66.7)

10 (24.4)

7 (15.6)

21 (33.9)

0.026

 Admission to ICU, n (%)

54 (35.1)

5 (83.3)

15 (36.6)

11 (24.4)

23 (37.1)

0.032

 Postpartum haemorrhage, n (%)

16 (10.4)

1 (16.7)

3 (7.3)

8 (17.8)

4 (6.5)

0.197

 Uterine fatigue, n (%)

26 (16.9)

1 (16.7)

5 (12.2)

10 (22.2)

10 (16.1)

0.642

 Heart failure, n (%)

23 (14.9)

4 (66.7)

1 (2.4)

6 (13.3)

12 (19.4)

<  0.001

MODS, n (%)

8 (5.2)

3 (50)

1 (2.4)

2 (4.4)

2 (3.2)

0.003

 Cardiac arrest, n (%)

1 (0.6)

0 (0)

0 (0)

1 (2.2)

0 (0)

0.607

 Maternal death, n (%)

5 (3.2)

3 (50)

1 (2.4)

0 (0)

1 (1.6)

<  0.001

Foetal outcome

 Premature infants (< 37 weeks), n (%)

66 (42.9)

4 (66.7)

13 (31.7)

17 (37.8)

32 (51.6)

0.122

 (34 ~ 37 weeks), n (%)

30 (19.5)

2 (33.3)

4 (9.8)

7 (15.6)

17 (27.4)

0.088

 (< 34 weeks), n (%)

36 (23.4)

2 (33.3)

9 (22)

10 (22.2)

15 (24.2)

0.897

 Birth weight of the newborn, mean ± SD

2334.9 ± 814.6

2124.0 ± 837.4

2341.3 ± 799.3

2522.6 ± 974.0

2243.8 ± 718.8

0.374

 LBW, n (%)

44 (28.6)

3 (50)

8 (19.5)

7 (15.6)

26 (41.9)

0.004

 VLBW, n (%)

20 (13.0)

0 (0)

7 (17.1)

3 (6.7)

10 (16.1)

0.367

 ELBW, n (%)

5 (3.2)

1 (16.7)

1 (2.4)

3 (6.7)

0 (0)

0.031

 SGA, n (%)

94 (61.0)

4 (66.7)

25 (61)

17 (37.8)

48 (77.4)

<  0.001

 Therapeutic abortion

15 (9.7)

0 (0)

7 (17.1)

5 (11.1)

3 (4.8)

0.204

 Intrauterine death, n (%)

7 (4.5)

0 (0)

1 (2.4)

5 (11.1)

1 (1.6)

0.132

 Missed abortion, n (%)

1 (0.6)

0 (0)

0 (0)

1 (2.2)

0 (0)

0.589

 Neonatal death (< 1 week), n (%)

3 (1.9)

0 (0)

1 (2.4)

1 (2.2)

1 (1.6)

0.43

  1. LBW low birth weight (> 1500 g, < 2500 g); VLBW very low birth weight (1000–1500 g); ELBW extremely low birth weight (< 1000 g); SGA small for gestational age; MODS multiple organ dysfunction syndrome