Nontargeted metabolomics reveals the potential mechanism underlying the association between birthweight and metabolic disturbances

Table 3 Correlation of line-shaped metabolites and blood index in maternal blood

		Serotonin		13(S)-HODE		LysoPC(P-18:1)		MG(0:0/24:6)
		r	P	r	P	r	P	r	P
BMI	Model1	0.259	0.037	0.462	< 0.001	-0.077	0.544	0.024	0.848
	Model2	0.193	0.140	0.441	< 0.001	-0.073	0.580	0.115	0.380
Weight Gain	Model1	0.191	0.128	0.404	0.001	-0.135	0.283	-0.120	0.341
	Model2	0.230	0.076	0.400	0.002	-0.133	0.312	-0.155	0.238
HbA1c	Model1	0.212	0.139	0.125	0.388	0.047	0.748	-0.055	0.705
	Model2	0.107	0.483	0.259	0.086	0.060	0.693	-0.084	0.583
FBG	Model1	-0.227	0.071	-0.157	0.216	0.248	0.048	0.073	0.567
	Model2	-0.188	0.155	-0.129	0.328	0.186	0.159	0.033	0.805
HDL-C	Model1	-0.190	0.129	-0.139	0.268	0.286	0.021	-0.073	0.563
	Model2	-0.236	0.069	-0.152	0.247	0.192	0.142	-0.145	0.270
LDL-C	Model1	-0.076	0.545	-0.152	0.228	0.166	0.185	0.118	0.350
	Model2	0.016	0.906	-0.041	0.758	0.216	0.098	0.044	0.741
FFA	Model1	0.312	0.011	0.069	0.583	-0.111	0.380	0.313	0.011
	Model2	0.303	0.019	0.052	0.695	-0.150	0.251	0.315	0.014
Leptin	Model1	-0.010	0.937	0.170	0.181	-0.084	0.511	-0.182	0.151
	Model2	-0.045	0.735	0.092	0.487	-0.013	0.920	-0.180	0.172
Adiponectin	Model1	-0.126	0.321	-0.284	0.023	0.097	0.445	-0.048	0.706
	Model2	0.000	0.997	-0.079	0.552	0.174	0.187	-0.018	0.893
HCY	Model1	0.361	0.003	0.258	0.038	-0.118	0.350	-0.032	0.800
	Model2	0.244	0.061	0.111	0.397	-0.211	0.106	-0.075	0.571

Model 1 is non-adjusted
Model 2 is adjusted for maternal age, parity, GDM and gestational age, and fetal sex

ISSN: 1471-2393