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Table 3 Eligible number of patients, total costs, and budget impact of adding TXA to standard care treatment for PPH management

From: Cost-effectiveness and budget impact of adding tranexamic acid for management of post-partum hemorrhage in the Indian public health system

 

2021

2022

2023

2024

2025

Total number of PPH patients in India

643,226

676,439

666,150

596,409

471,710

Current Scenario—patients eligible for available standard care

643,226 (100%)

676,439 (100%)

666,150 (100%)

596,409 (100%)

471,710 (100%)

Bottom-up uptake of TXA intervention

119,704 (19%)

348,637 (52%)

666,150 (100%)

596,409 (100%)

471,710 (100%)

Standard treatment care uptake with TXA introduction

523,521 (81%)

327,803 (48%)

0 (0%)

0 (0%)

0 (0%)

 

The total cost of PPH management with tranexamic acid addition

The total cost of PPH management without tranexamic acid addition

Budget impact (difference)

Percentage impact (% difference)

2021

INR 4,212,816,600

USD 60,670,189

INR 4,187,661,060

USD 60,307,916

INR 25,155,540

USD 362,273

0.6%

2022

INR 4,477,159,957

USD 64,477,087

INR 4,403,894,864

USD 63,421,972

INR 73,265,093

USD 1,055,115

1.7%

2023

INR 4,476,894,328

USD 64,473,261

INR 4,336,904,772

USD 62,457,225

INR 139,989,556

USD 2,016,037

3.2%

2024

INR 4,008,198,438

USD 57,723,414

INR 3,882,864,695

USD 55,918,441

INR 125,333,742

USD 1,804,973

3.2%

2025

INR 3,170,151,163

USD 45,654,413

INR 3,071,022,610

USD 44,226,830

INR 99,128,552

USD 1,427,584

3.2%

Cumulative

INR 20,345,220,485

USD 292,998,365

INR 19,882,348,001

USD 286,332,383

INR 462,872,485

USD 6,665,982

2.3%