Table 3 Subgroup analyses for the association between FBG and RPL

Region

 Asia

7

2.48 [0.33, 4.63]

91

 < 0.00001

6.31

0.18

36.6

 Africa

2

11.63 [-7.58, 30.84]

96

 < 0.00001

 Europe

2

-1.74 [-9.36, 5.88]

88

0.003

 America

2

-1.08 [-4.24, 2.07]

34

0.22

 Middle East

6

3.49 [-0.15, 7.13]

74

0.002

Definition of RPL

  >  = 2

10

3.82 [1.17, 6.47]

94

 < 0.00001

2.89

0.09

65.4

  >  = 3

9

1.27 [0.00, 2.54]

16

0.30

Matched confounders

 No

8

1.09 [-0.84, 3.02]

87

 < 0.00001

2.64

0.10

62.2

 Yes

11

4.20 [0.98, 7.41]

89

 < 0.00001

Measurement timing

 During pregnancy

3

2.12 [-2.50, 6.73]

88

0.0002

0.06

0.80

0

 Not during pregnancy

16

2.75 [0.80, 4.70]

88

 < 0.00001

Exclusion of known factors

 Yes

14

2.66 [0.54, 4.77]

9

 < 0.00001

0.02

0.89

0

 No

5

2.88 [0.72, 5.03]

62

0.03