Clinical features at the time of non-hysteroscopic myomectomy before pregnancy, which affect adverse pregnancy outcomes: a retrospective cohort study

Table 3 Obstetric outcomes according to the number of uterine myomas removed

	Number of uterine myomas removed (single)(N=102)	Number of uterine myomas removed (≥2)(N=146)	p-value	Unadjusted odds ratio (95% CI)(Reference: single)	p-value	Adjusted odds ratio (95% CI)^a(Reference: single)	p-value
GA at delivery (weeks)*	37.5 ± 2.6	37.8 ± 2.2	0.351
Birthweight (g)*	3046 ± 570	3011 ± 605	0.651
Placental weight (g)*	718 ± 233	688 ± 192	0.257
Preterm birth^†	14 (13.9)	16 (11.0)	0.317	0.77 (0.36-1.66)	0.506	0.66 (0.24-1.80)	0.413
Emergent delivery^†	16 (15.8)	27 (18.5)	0.358	1.21 (0.61-2.38)	0.589	0.93 (0.42-2.07)	0.862
Placental accreta/increta^†	4 (3.9)	9 (6.2)	0.317	1.61 (0.48-5.38)	0.439	2.15 (0.55-8.36)	0.270
Transfusion^†	19 (18.6)	48 (32.9)	0.009	2.14 (1.17-3.92)	0.014	2.41 (1.20-4.86)	0.014
SGA^†	4 (3.9)	11 (7.5)	0.184	2.00 (0.62-6.46)	0.248	2.73 (0.68-10.94)	0.155
NICU admission^†	15 (14.9)	26 (17.9)	0.324	1.25 (0.63-2.51)	0.524	1.18 (0.51-2.73)	0.707
Composite morbidity ^b^†	9 (8.8)	11 (7.5)	0.444	0.84 (0.34-2.11)	0.714	0.62 (0.20-1.91)	0.404

GA Gestational age, SGA Small for gestational age, NICU neonatal intensive care unit; ^aAll outcomes were adjusted for maternal age, body mass index, method of conception, twin pregnancy, Interval time between myomectomy and pregnancy, myomectomy method, sum of the diameters of which the three biggest uterine myomas, and type of uterine myomas;^bComposite morbidity includes neonatal sepsis, retinopathy of prematurity, patent ductus arteriosus, respiratory distress syndrome, bronchopulmonary dysplasia and necrotizing enterocolitis; *Data given as mean ± SD, ^†Data given as n (%)

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