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Table 1 Characteristics of the patients and cycles

From: Frozen-thawed embryo transfer in modified natural cycles: a retrospective analysis of pregnancy outcomes in ovulatory women with vs. without spontaneous luteinizing hormone surge

 

Overall sample (n = 1897)

LH surge (n = 920)

Without LH surge (n = 977)

P

Age (years) mean ± SD

33.32 ± 4.62

33.07 ± 4.56

33.55 ± 4.67

0.258

 ≥ 37, n (%)

446 (23.51%)

198 (21.5%)

248 (25.4%)

0.584

BMI (kg/m2) mean ± SD

21.42 ± 5.52

21.38 ± 2.76

21.55 ± 7.1

0.226

 18, n (%)

156 (8.22%)

75 (8.15%)

81 (8.29%)

 

 18 ≤  ~  < 24, n (%)

1450 (76.43%)

705 (76.63%)

745 (76.26%)

 

 24 ≤  ~  < 28, n (%)

242 (12.75%)

118 (12.83%)

124 (12.69%)

 

 ≥ 28, n (%)

49 (2.6%)

22 (2.39%)

27 (2.76%)

 

Infertility type, n (%)

   

0.781

 Primary

1000 (52.71%)

488 (53.1%)

512 (52.4%)

 

 Secondary

897 (47.29%)

432 (46.9%)

465 (47.6%)

 

Infertility cause, n (%)

   

0.663

 Tubal

1252 (66%)

618 (67.2%)

634 (64.9%)

 

 Decreased ovarian reserve

74 (3.9%)

36 (3.9%)

38 (3.9%)

 

 Endometriosis

231 (12.18%)

111 (12.1%)

120 (12.3%)

 

 Male factors

279 (14.71%)

118 (12.8%)

161 (16.5%)

 

 Others

61 (3.21%)

37 (4%)

24 (2.4%)

 

Infertility duration (years), median (range)

2 (0–20)

2 (0–20)

3 (0–19)

0.711

Antral follicle counts, mean ± SD

6.19 ± 5.8

6.24 ± 5.85

6.13 ± 5.76

0.221

Basal hormone level, mean mean ± SD

 FSH (IU/L)

5.15 ± 1.62

4.93 ± 1.20

5.73 ± 1.26

0.462

 LH (IU/L)

5.24 ± 2.36

5.78 ± 1.99

4.21 ± 2.23

0.567

 E2 (pg/ml)

36.98 ± 14.53

36.31 ± 11.40

38.63 ± 17.57

0.564

 Progesterone (ng/ml)

0.28 ± 0.14

0.25 ± 0.11

0.32 ± 0.15

0.187

Hormone level, hCG day, mean ± SD

 FSH (IU/L)

7.48 ± 3.96

10.06 ± 3.92

5.1 ± 1.94

 < 0.001

 LH (IU/L)

23.6 ± 14.44

35.08 ± 12.6

12.8 ± 3.85

 < 0.001

 E2 (pg/ml)

264.26 ± 92.93

257.99 ± 91.39

270.18 ± 94.02

0.909

 Progesterone (ng/ml)

0.45 ± 0.23

0.59 ± 0.21

0.32 ± 0.16

 < 0.001

Hormone level, FET day, mean ± SD

 E2 (pg/ml)

115.1 ± 52.23

110.7 ± 47.73

119.07 ± 55.73

0.186

 Progesterone (ng/ml)

18.33 ± 7.2

18.02 ± 6.93

18.61 ± 7.43

0.127

Endometrium thickness (mm) mean ± SD

10.75 ± 2.08

10.8 ± 2.1

10.7 ± 2.1

0.283

 7, n (%)

114 (6%)

56 (6.09%)

58 (5.94%)

 

Fertilization type, n (%)

   

0.613

 IVF

1275 (67.21%)

621 (67.5%)

654 (67%)

 

 ICSI

622 (32.79%)

299 (32.5%)

323 (33%)

 

Cryopreservation time (day), mean ± SD

72.73 ± 2.87

73.26 ± 2.59

72.47 ± 3.11

0.663

Number of embryo transferred, n (%)

   

0.282

 1

510 (26.88%)

236 (25.65%)

274 (28.05%)

 

 2

1387 (73.12%)

684 (74.35%)

703 (71.95%)

 

Embryo stage, n (%)

   

0.336

 Cleavage

1585 (83.55%)

758 (82.39%)

827 (84.65%)

 

 Blastocyst

312 (16.45%)

162 (17.61%)

150 (15.35%)

 

Embryo quality, good (%)

96.3%

96.5%

96.2%

0.236