The impact of oocytes containing smooth endoplasmic reticulum aggregates on assisted reproductive outcomes: a cohort study

Table 3 Pregnancy and neonatal outcomes of all patients in SERa + and SERa– cycles

Characteristic	SERa + cycles	SERa—cycles	χ²/t	P-value^*
No. of embryo transfer cycles, n	372	359	-	-
No. of embryo transferred,%			0.078	0.780
1	24.73 (92/372)	25.63 (92/359)
2 or 3	75.27 (280/372)	74.37 (267/359)
Implantation rate, %	31.67 (210/663)	29.25 (189/645)	0.868	0.352
Clinical pregnancy rate, %	44.89 (167/372)	42.34 (152/359)	0.484	0.487
Singleton pregnancy rate,%	31.50 (117/372)	30.60 (110/359)	0.056	0.813
Twins pregnancy rate,%	12.40 (46/372)	10.90 (39/359)	0.401	0.527
Ectopic pregnancy rate, %	1.10 (4/372)	0.80 (3/359)	0.000	1.000^**
Live birth rate, %	77.80 (129/167)	79.60 (121/152)	0.111	0.739
Singleton	59.30 ( 99/167)	67.10 (102/152)	2.090	0.148
Twins	18.00 (30/167)	12.50 (19/152)	1.827	0.176
Spontaneous abortion rate, %	17.40 (29/167)	15.80 (24/152)	0.143	0.706
No. of lost follow-up	5	4	-	-
Weeks of gestation, wk	38.28 ± 1.93	38.23 ± 1.72	0.824	0.361
No. of newborns, n	159	140	-	-
Premature delivery rate, %	10.90 (14/129)	15.70 (19/121)	1.282	0.258
Weight of singleton births, kg	3.14 ± 0.60	3.09 ± 0.50	-0.651	0.516
Weight of twin births, kg	2.50 ± 0.45	2.63 ± 0.84	1.036	0.303
Rate of newborn malformation rate, %	1.90 (3/159)	0.70 (1/140)	0.142	0.707^**

Note: Data are presented as mean ± SD for continuous variables and % (n/N) for categorical variables
Implantation rate = No. of gestational sacs/ No. of transfer embryos, clinical pregnancy rate = No. of pregnancy cycles/No. of embryo transfer cycles, ectopic pregnancy rate = No. of ectopic pregnancy cycles/ No. of embryo transfer cycles, live birth rate = No. of live birth cycles/ No. of pregnancy cycles, spontaneous abortion rate = No. of early and late spontaneous abortion cycles/ No. of clinical pregnancy cycles, premature delivery rate = No. of premature cycles/ No. of live birth cycles, newborn malformation rate = No. of malformed newborns/ No. of live births
Premature delivery is defined as babies born from 28 to 37 weeks
^*P value calculated with χ² test or t-test as appropriate
^** P value calculated with continuity correction χ² test

ISSN: 1471-2393