The effect of vitamin D supplementation on oxidative stress and inflammatory biomarkers in pregnant women: a systematic review and meta-analysis of clinical trials

Table 2 Publication bias assessment by Egger’s statistical test for effect of vitamin D supplementation on the levels of 25(OH)D, CB 25(OH)D, hs-CRP, MDA, TAC and GSH

Markers	NO of interventions	NO of participants	Coefficient	Std. Err	t	P	95% CI
Markers	NO of interventions	NO of participants	Coefficient	Std. Err	t	P	LL	UL
25(OH)D	15	1061	7.56	1.33	5.65	< 0.001	4.67	10.45
CB 25(OH)D	3	162	12.06	32.81	0.37	0.77	-404.05	429.05
hs-CRP	11	670	6.05	4.63	1.31	0.22	-4.42	16.53
TAC	9	543	15.35	1.32	11.63	< 0.001	12.23	18.47
MDA	6	370	-21.99	3.32	6.62	0.003	-31.21	-12.77
GSH	9	539	12.73	1.30	9.78	< 0.001	9.65	15.81

Abbreviations: 25(OH)D 25-hydroxyvitamin D3, CB Cord Blood, CI Confidence interval, hs-CRP High-sensitivity C-reactive protein, TAC Total antioxidant capacity, MDA Malondialdehyde, GSH Glutathione

ISSN: 1471-2393