| LC/GDM (N = 20) | Con/GDM (N = 80) | Con/Healthy (N = 80) | p-value |
---|---|---|---|---|
Maternal characteristics | ||||
Maternal age(years) | ||||
 Mean (SD) | 31.4 ± 3.98 | 30.1 ± 3.38 | 31.1 ± 3.59 | 0.147 |
 N (%) |  |  |  | 1.000 |
   ≤ 35 | 19 (95) | 76 (95) | 76 (95) |  |
   > 35 | 1 (5) | 4(5) | 4 (5) | |
Parity, n (%) | Â | Â | Â | 1.000 |
 Nulliparous | 18 (90) | 72 (90) | 72 (90) |  |
 Multiparous | 2 (10) | 8 (10) | 8 (10) | |
Education, n (%) | Â | Â | Â | 0.595 |
 High school and lower | 3 (15) | 15 (18.75) | 19 (23.75) |  |
 College and above | 17 (85) | 65 (81.25) | 61 (76.25) | |
Pre-pregnancy BMI (kg/m2) | ||||
 Mean (SD) | 19.1 ± 2.00 | 19.7 ± 2.32 | 19.5 ± 2.30 | 0.647 |
 n (%) |  |  |  | 1.000 |
  < 18.5 | 10 (50) | 40 (50) | 40 (50) |  |
  18.5–23.9 | 9 (45) | 36 (45) | 36 (45) | |
  ≥ 24 | 1 (5) | 4 (5) | 4 (5) | |
Race, n (%) | Â | Â | Â | 1.000 |
 Han | 20 (100) | 78 (97.5) | 77 (96.25) |  |
 Non-Han | 0 (0) | 2 (2.5) | 3 (3.75) | |
Family history of diabetes, n (%) | Â | Â | Â | 1.000 |
 NO | 18 (90) | 72 (90) | 72 (90) |  |
 Yes | 2 (10) | 8 (10) | 8 (10) |  |
Blood pressure | ||||
 Systolic (mmHg) | 107.8 ± 16.7 | 112.7 ± 11.1 | 109.2 ± 11.5 | 0.102 |
 Diastolic (mmHg) | 69.6 ± 12.9 | 70.6 ± 11.1 | 70.2 ± 10.0 | 0.923 |
Lipid profile | Â | Â | Â | Â |
 TG (mmol/L) | 1.28 ± 0.79 | 1.32 ± 0.50 | 1.21 ± 0.44 | 0.345 |
 TC (mmol/L) | 4.31 ± 0.94 | 4.57 ± 0.71b | 4.19 ± 0.82 |  < 0.05 |
 LDLC (mmol/L) | 2.45 ± 0.81 | 2.46 ± 0.65 | 2.23 ± 0.75 | 0.104 |
 HDLC (mmol/L) | 2.19 ± 0.49 | 2.08 ± 0.49 | 1.99 ± 0.44 | 0.182 |
Gestational weight gain | ||||
 Gestational weeks (wk) | 13.2 ± 3.0 | 12.5 ± 1.2 | 12.5 ± 0.9 | 0.125 |
 1st trimester | 1.95 ± 2.72 | 2.18 ± 2.60 | 1.92 ± 2.32 | 0.798 |
 Gestational week interval (wk) | 16.4 ± 2.6 | 16.3 ± 1.5 | 16.3 ± 1.2 | 0.945 |
 2nd trimester | 5.72 ± 2.08a | 7.01 ± 2.41b | 8.33 ± 2.56c |  < 0.001 |
 Gestational week interval (wk) | 9.5 ± 1.5a | 10.8 ± 1.2 | 10.8 ± 1.6c |  < 0.05 |
 3rd trimester | 3.11 ± 1.75 | 3.31 ± 2.30b | 5.26 ± 2.54c |  < 0.001 |
 Gestational weeks (wk) | 39.1 ± 0.7 | 39.2 ± 1.6 | 39.7 ± 1.6 | 0.072 |
 Total weight gain | 10.8 ± 3.93 | 12.5 ± 4.42b | 15.5 ± 4.45c |  < 0.001 |
Preeclampsia, n (%) | Â | Â | Â | 0.792 |
 No | 19 (95) | 78 (97.5) | 78 (97.5) |  |
 Yes | 1 (5) | 2 (2.5) | 2 (2.5) |  |
Thyroid dysfunction | Â | Â | Â | 0.904 |
 No | 19 (95) | 75 (93.75) | 74 (92.5) |  |
 Yes | 1 (5) | 5 (6.25) | 6 (7.5) |  |
Mode of delivery | Â | Â | Â | 0.102 |
 Vaginal birth | 6 (30) | 47 (58.75) | 42 (52.5) |  |
 Cesarean section | 14 (70) | 33 (41.25) | 38 (47.5) |  |
Gestational age (weeks) | 39.1 ± 0.7 | 39.2 ± 1.6 | 39.7 ± 1.6 | 0.072 |
Child characteristics | ||||
Birth weight (g) | 3113.4 ± 289.5 | 3193.7 ± 493.4 | 3267.9 ± 471.3 | 0.354 |
LGA, n (%) | 0 (0) | 4 (5) | 5 (6.25) | 0.534 |
SGA, n (%) | 0 (0) | 2 (2.5) | 1 (1.25) | 0.690 |