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Table 3 Characteristics (independent variables) dichotomized according to Cesarean delivery and vaginal delivery (dependent variable) on bivariate or crude analysis and results following adjusted analysis incorporating all significant (p < 0.05) independent variables on crude analysis

From: HbA1c at term delivery and adverse pregnancy outcome

Variable

LGA (n = 99)

Non LGA (n = 901)

P Value

RR (95% CI)

Multivariable Logistic Regression Analysis

AOR (95%CI)

P value

HbA1c (%)

5.4[5.1–5.6]

5.3[5.1–5.6]

0.17

 

1.43 (0.93–2.18)

0.101

Gestational age (weeks, mean ± SD)

39.1 ± 1.1

39.0 ± 1.1

0.55

   

Age (years, mean ± SD)

31.0 ± 4.5

30.6 ± 4.6

0.43

   

Parity category

  

0.068

   

 0

29 (29.3%)

367 (40.7%)

    

 1

37 (37.4%)

288 (32.0%)

    

 2

16 (16.2%)

150 (16.6%)

    

  ≥ 3

17 (17.2%)

96 (10.7%)

    

Previous miscarriage

23 (23.2%)

189 (21.0%)

0.60

1.11 (0.76–1.62)

  

Ethnicity

  

0.81

   

 Malay

66 (66.7%)

555 (61.6%)

    

 Chinese

11 (11.1%)

116 (12.9%)

    

 Indian

10 (10.1%)

106 (11.8%)

    

 Others

12 (12 .1%)

124 (13.8%)

    

BMI (kg/m2, mean ± SD)

29.9 ± 4.8

28.8 ± 4.9

0.022

 

1.04 (1.00–1.09)

0.048

Hemoglobin < 11 g/dL

30 (30.3%)

182 (20.2%)

0.02

1.50 (1.08–2.08)

1.74 (1.09–2.78)

0.021

Medical and obstetric history

Diabetes in pregnancy

23 (23.2%)

219 (24.3%)

0.81

0.96 (0.66–1.39)

  

  Antiglycemic

7 (7.1%)

63 (7.0%)

0.98

1.01 (0.48–2.15)

  

  Asthma

5 (5.1%)

48 (5.3%)

0.91

0.95 (0.39–2.33)

  

Hypertension in pregnancy

6 (6.1%)

43 (4.8%)

0.57

1.27 (0.56–2.91)

  

Group B streptococcus carriage

12 (12.1%)

47 (5.2%)

0.006

2.32 (1.28–4.23)

2.71 (1.37–5.38)

0.004

Thalassemia trait

0 (0.0%)

10 (1.1%)

0.29

*

  

HIV or Hepatitis B infection

1 (1.0%)

8 (0.9%)

0.61

1.14 (0.14–9.00)

  

Previous Cesarean

17 (17.2%)

148 (16.4%)

0.85

1.05 (0.66–1.65)

  

Induction of labor

16 (16.2%)

190 (21.1%)

0.25

0.77 (0.48–1.17)

  
  1. Values are stated as mean ± standard deviation, median [interquartile range] or n (%). Crude analysis by t test for continuous data, Mann–Whitney U test for non-parametric data and Chi Square test for categoric variable, Adjustment made utilizing multivariable binary logistic regression analysis of significant independent variable with adjusted results shown if variable incorporated in the model