Table 1 Maternal characteristics of the study cohorts
Cohorts | NSAID | Comparison |
|---|---|---|
GW at first contact, n | 1092 | 1154 |
Median (IQR) | 12.4 (7.7–20.9) | 7.7 (6–10.1) |
Age (years), n | 1091 | 1154 |
Median (IQR), (min-max) | 33 (30–36) (15–49) | 32 (28–35) (17–45) |
Pre-pregnancy BMI, n | 1061 | 1095 |
Median, (kg/m2), (IQR) | 23.1 (20.9–26.7) | 22.8 (20.7–26.2) |
Educational level, n | 779 | 704 |
≤ 9 years, n (%) | 4 (0.5) | 8 (1.1) |
>  9 and ≤ 13.5 years, n (%) | 209 (26.8) | 229 (32.5) |
Acadamic degree, n (%) | 342 (43.9) | 285 (40.5) |
Smoking, n | 1089 | 1144 |
No, n (%) | 922 (84.7) | 910 (79.5) |
≤ 5 cig/day, n (%) | 45 (4.1) | 64 (5.6) |
>  5 cig/day, n (%) | 122 (11.2) | 170 (14.9) |
Alcohol, n | 1089 | 1142 |
No, n (%) | 959 (88.1) | 964 (84.4) |
≤ 1 drink/day, n (%) | 89 (8.2) | 107 (9.4) |
>  1 drink/day, n (%) | 41 (3.8) | 71 (6.2) |
Pregnancy wanted, n | 863 | 963 |
Yes, n (%) | 829 (96.1) | 863 (89.6) |
Indifferent, n (%) | 23 (2.7) | 79 (8.2) |
No, n (%) | 11 (1.3) | 21 (2.2) |
Previous pregnancies, n | 1089 | 1149 |
0, n (%) | 430 (39.5) | 476 (41.4) |
1, n (%) | 363 (33.3) | 366 (31.9) |
2, n (%) | 161 (14.8) | 169 (14.7) |
≥ 3, n (%) | 135 (12.4) | 138 (12) |
Previous deliveries, n | 1089 | 1147 |
0, n (%) | 530 (48.7) | 561 (48.9) |
1, n (%) | 394 (36.2) | 380 (33.1) |
2, n (%) | 125 (11.5) | 139 (12.1) |
≥ 3, n (%) | 40 (3.7) | 67 (5.8) |
Previous spontaneous abortions, n | 1087 | 1143 |
0, n (%) | 876 (80.6) | 989 (86.5) |
1, n (%) | 143 (13.2) | 109 (9.5) |
≥ 2, n (%) | 68 (6.3) | 45 (3.9) |
Previous children with birth defect, n | 1088 | 1144 |
0, n (%) | 1059 (97.3) | 1118 (97.7) |
1, n (%) | 25 (2.3) | 23 (2) |
≥ 2, n (%) | 4 (0.4) | 3 (0.3) |