Analyte | Established interval | Gestational age | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
≤ 8 W | 8 W+1-12 W | 12 W+1-16 W | 16 W+1-20 W | 20 W+1-24 W | 24 W+1-28 W | 28 W+1-32 W | 32 W+1-36 W | 36 W+1-40 W | |||
TC (mmol/L) | |||||||||||
Mean | 3.36–5.69 | 4.02 | 4.19 | 4.67 | 5.12 | 5.66 | 6.03 | 6.33 | 6.38 | 6.60 | |
Lower limit | 2.82 (2.68–3.01) | 3.10 (2.88–3.25) | 3.41 (3.28–3.62) | 3.82 (3.46–4.05) | 3.97 (3.15–4.25) | 4.28 (3.78–4.56) | 4.55 (4.14–4.77) | 4.57 (4.46–4.66) | 4.58 (4.28–4.98) | ||
Upper limit | 5.25 (5.02–6.62) | 5.30 (5.15–5.77) | 6.08 (5.71–6.32) | 6.86 (6.49–7.02) | 7.40 (7.11–7.61) | 8.15 (7.62–8.43) | 8.10 (7.91–8.48) | 8.42 (8.00–8.90) | 9.23 (8.25–10.97) | ||
n% | 14.2 | 5.8 | 4.2 | 20.0 | 45.0 | 60.0 | 70.8 | 69.2 | 75.8 | ||
TG (mmol/L) | |||||||||||
Median | 0.40–1.69 | 0.72 | 1.06 | 1.43 | 1.73 | 2.02 | 2.28 | 2.63 | 2.98 | 3.23 | |
Lower limit | 0.34 (0.33–0.40) | 0.57 (0.44–0.64) | 0.81 (0.75–0.88) | 0.82 (0.68–1.03) | 1.00 (0.94–1.10) | 1.23 (1.15–1.32) | 1.35 (1.29–1.58) | 1.67 (1.59–1.90) | 2.02 (1.56–2.14) | ||
Upper limit | 2.16 (1.62–2.33) | 2.30 (1.96–3.37) | 3.08 (2.41–3.31) | 3.99 (3.01–5.16) | 4.28 (3.13–5.85) | 4.86 (4.13–5.27) | 5.76 (4.90–8.03) | 6.46 (5.73–6.97) | 6.27 (6.01–7.69) | ||
n% | 6.7 | 5.0 | 30.0 | 50.8 | 63.3 | 79.2 | 88.3 | 95.0 | 97.5 | ||
HDL-C (mmol/L) | |||||||||||
Mean | 1.00–2.10 | 1.45 | 1.63 | 1.81 | 1.93 | 2.04 | 2.10 | 2.04 | 1.98 | 2.03 | |
Lower limit | 0.91 (0.73–0.98) | 1.04 (0.86–1.10) | 1.15 (0.94–1.26) | 1.32 (1.14–1.35) | 1.26 (1.19–1.35) | 1.37 (1.06–1.49) | 1.29 (1.08–1.51) | 1.23 (0.85–1.36) | 1.19 (0.94–1.37) | ||
Upper limit | 2.28 (1.97–2.44) | 2.38 (2.19–2.44) | 2.56 (2.48–2.63) | 2.62 (2.49–2.78) | 2.64 (2.59–2.83) | 2.68 (2.56–3.32) | 2.69 (2.59–2.95) | 2.71 (2.56–3.45) | 2.95 (2.55–3.98) | ||
n% | 5.8 | 6.7 | 15.0 | 39.0 | 41.7 | 52.5 | 43.3 | 35.0 | 37.5 | ||
LDL-C (mmol/L) | |||||||||||
Median | < 3.37 | 2.17 | 2.15 | 2.41 | 2.62 | 3.00 | 3.31 | 3.63 | 3.59 | 3.59 | |
Upper limit | 3.17 (3.03–4.41) | 3.03 (2.74–3.12) | 3.19 (3.13–3.63) | 3.89 (3.61–4.23) | 4.40 (4.10–4.49) | 4.94 (4.42–5.40) | 5.00 (4.87–5.18) | 5.16 (4.85–5.56) | 5.56 (5.08–6.05) | ||
n% | 0.0 | 0.0 | 0.0 | 9.2 | 28.3 | 40.8 | 59.2 | 54.2 | 55.8 | ||
Apo-A1 ( g/L) | |||||||||||
Median | 1.20–1.90 | 1.52 | 1.78 | 2.03 | 2.14 | 2.23 | 2.24 | 2.25 | 2.22 | 2.28 | |
Lower limit | 1.00 (0.93–1.15) | 1.28 (1.08–1.37) | 1.38 (1.24–1.55) | 1.60 (1.32–1.68) | 1.61 (1.40–1.75) | 1.73 (1.39–1.80) | 1.68 (1.53–1.74) | 1.63 (1.28–1.83) | 1.82 (1.36–1.85) | ||
Upper limit | 2.11 (1.87–2.24) | 2.30 (2.12–2.33) | 2.42 (2.37–2.49) | 2.43 (2.39–2.62) | 2.58 (2.55–2.84) | 2.87 (2.71–2.99) | 2.77 (2.61–3.50) | 2.91 (2.69–3.10) | 2.85 (2.64–3.00) | ||
n% | 3.3 | 31.7 | 65.0 | 80.8 | 87.5 | 90.0 | 90.0 | 90.0 | 91.7 | ||
Apo-B ( g/L) | |||||||||||
Median | 0.75–1.50 | 0.66 | 0.68 | 0.78 | 0.88 | 0.99 | 1.08 | 1.19 | 1.20 | 1.22 | |
Lower limit | 0.40 (0.39–0.46) | 0.44 (0.32–0.46) | 0.48 (0.40–0.54) | 0.53 (0.43–0.58) | 0.61 (0.45–0.69) | 0.64 (0.56–0.73) | 0.74 (0.69–0.79) | 0.78 (0.69–0.83) | 0.78 (0.71–0.83) | ||
Upper limit | 1.16 (0.99–1.41) | 1.00 (0.92–1.22) | 1.12 (1.08–1.32) | 1.37 (1.29–1.42) | 1.51 (1.39–1.61) | 1.58 (1.52–1.81) | 1.66 (1.64–1.75) | 1.71 (1.67–1.98) | 1.94 (1.63–2.22) | ||
n% | 67.5 | 63.3 | 37.5 | 25.0 | 9.2 | 10.0 | 13.3 | 14.2 | 20.0 | ||
Urea (mmol/L) | |||||||||||
Median | 2.60–7.50 | 2.99 | 2.53 | 2.50 | 2.51 | 2.60 | 2.67 | 2.66 | 2.68 | 2.94 | |
Lower limit | 1.97 (1.79–2.08) | 1.75 (0.60–1.81) | 1.57 (1.31–1.75) | 1.51 (1.18–1.63) | 1.60 (1.34–1.89) | 1.71 (1.51–1.97) | 1.68 (1.59–1.79) | 1.50 (1.35–1.77) | 1.91 (1.89–2.04) | ||
Upper limit | 4.73 (4.49–6.61) | 3.83 (3.54–5.05) | 4.11 (3.67–4.56) | 4.04 (3.37–4.85) | 3.87 (3.65–4.20) | 4.55 (3.82–4.72) | 3.98 (3.82–4.07) | 4.29 (3.88–5.04) | 4.77 (4.05–5.34) | ||
n% | 25.0 | 52.5 | 58.3 | 56.7 | 48.3 | 39.2 | 43.3 | 43.3 | 29.2 | ||
Crea (μmol/L) | |||||||||||
Median | 41.0–73.0 | 46.4 | 41.9 | 40.4 | 40.2 | 39.9 | 40.5 | 41.4 | 42.4 | 45.2 | |
Lower limit | 37.1 (30.8–38.1) | 33.2 (31.8–34.9) | 32.1 (28.4–33.0) | 30.0 (28.3–31.8) | 28.3 (26.4–32.6) | 30.3 (26.9–32.1) | 28.1 (27.3–32.1) | 29.3 (27.4–33.6) | 34.4 (33.4–35.3) | ||
Upper limit | 62.4 (58.8–64.0) | 54.9 (52.8–57.0) | 52.7 (50.4–56.0) | 51.9 (50.2–54.8) | 52.5 (49.2–64.9) | 55.8 (52.7–63.2) | 55.4 (52.5–61.7) | 55.6 (52.7–63.5) | 59.8 (57.4–63.7) | ||
n% | 10.8 | 40.8 | 52.5 | 56.7 | 59.2 | 51.7 | 46.7 | 40.8 | 20.8 | ||
Cys-C ( mg/L) | |||||||||||
Median | 0.59–1.03 | 0.75 | 0.70 | 0.71 | 0.76 | 0.79 | 0.86 | 0.94 | 1.08 | 1.25 | |
Lower limit | 0.63 (0.57–0.64) | 0.55 (049–0.57) | 0.57 (0.51–0.61) | 0.59 (0.56–0.62) | 0.62 (0.58–0.64) | 0.64 (0.60–0.67) | 0.73 (0.69–0.75) | 0.82 (0.77–0.85) | 0.96 (0.88–0.97) | ||
Upper limit | 0.95 (0.91–0.97) | 0.86 (0.83–0.96) | 0.88 (0.85–1.05) | 0.95 (0.92–0.99) | 1.03 (0.98–1.10) | 1.07 (1.05–1.14) | 1.33 (1.23–1.41) | 1.68 (1.51–1.76) | 1.72 (1.68–1.96) | ||
n% | 0.0 | 5.8 | 0.8 | 0.0 | 0.0 | 5.0 | 23.3 | 60.0 | 85.8 | ||
UA (μmol/L) | |||||||||||
Median | 150–350 | 225 | 201 | 207 | 215 | 219 | 227 | 235 | 256 | 281 | |
Lower limit | 145 (98–157) | 133 (105–143) | 141 (111–150) | 141 (115–154) | 150 (98–162) | 142 (106–162) | 145 (108–165) | 161 (146–175) | 167 (128–188) | ||
Upper limit | 326 (320–343) | 299 (277–315) | 308 (273–327) | 325 (306–375) | 326 (299–338) | 318 (309–408) | 331 (321–363) | 355 (343–412) | 464 (406–525) | ||
n% | 2.5 | 5.8 | 3.3 | 2.5 | 0.0 | 1.7 | 3.3 | 0.8 | 9.2 | ||
eGFR [mL/(min·1.73m2)] | |||||||||||
Median | 80–120 | 127 | 132 | 134 | 134 | 135 | 134 | 133 | 132 | 129 | |
Lower limit | 114 (112–116) | 120 (119–122) | 122 (117–124) | 121 (119–123) | 119 (112–124) | 117 (115–121) | 118 (117–121) | 117 (115–120) | 117 (109–118) | ||
Upper limit | 142 (139–148) | 144 (142–148) | 147 (143–152) | 148 (145–151) | 153 (147–156) | 152 (143–155) | 154 (146–157) | 149 (142–154) | 144 (141–146) | ||
n% | 83.3 | 95.8 | 95.0 | 95.8 | 95.0 | 94.2 | 96.2 | 93.3 | 90.0 |