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Table 5 Characteristics and clinical outcomes after propensity score matching between betamethasone group and betamethasone-free group

From: Betamethasone use and risk factors for pulmonary edema during the perinatal period: a single-center retrospective cohort study in Japan

 

Betamethasone-free group

Betamethasone group

  
 

n = 211

n = 211

P-values

SD

Background

 Maternal age, median [IQR]

32.0 [28.0, 36.0]

32.0 [29.0, 36.0]

0.745

0.025

 Body mass index, median [IQR]

23.0 [21.5, 26.0]

23.0 [21.0, 26.0]

0.798

0.002

 Nulliparity, n (%)

92 (43.6)

96 (45.5)

0.769

0.038

 Multiple pregnancies, n (%)

28 (13.3)

27 (12.8)

1

0.041

 Number of fetuses

  1, n (%)

183 (86.7)

184 (87.2)

0.925

0.052

  2, n (%)

26 (12.3)

24 (11.4)

  

  3, n (%)

2 (0.9)

3 (1.4)

  

  4, n (%)

0 (0.0)

0 (0.0)

  

Complications

 History of heart disease, n (%)

0 (0.0)

0 (0.0)

1

< 0.001

 Hypertensive disorder in pregnancy, n (%)

51 (24.2)

38 (18.0)

0.152

0.151

  Preeclampsia, n (%)

36 (17.1)

26 (12.3)

0.216

0.134

 Gestational diabetes mellitus, n (%)

10 (4.7) (15.3)

12 (5.7)

0.827

0.043

 Preterm labor with rupture of membrane, n (%)

35 (16.6)

38 (18.0)

0.797

0.038

Drug

 Ritodrine hydrochloride, n (%)

101 (47.9)

105 (49.8)

0.77

0.038

 Magnesium sulfate, n (%)

100 (47.4)

93 (44.1)

0.558

0.067

Clinical outcomes

 PE, n (%)

1 (0.5)

8 (3.8)

0.037

0.231

  1. Values are presented as median [interquartile range] and numbers (percentage)
  2. PE Pulmonary edema, IQR Interquartile range, ICU Intensive care unit, SD Standardized difference