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Table 4 Interaction between FT3/FT4 and TG levels for the risk of GDM*

From: The interactive effects of pre-pregnancy body mass index, thyroid function, and blood lipid levels on the risk of gestational diabetes mellitus: a crossover analysis

TG levels

Non-risk ratio (FT3/FT4 < 0.502)

Risk ratio (FT3/FT4 ≥ 0.502)

OR (95%CI) for risk ratio within category of blood lipid levels

AP (95%CI)

RERI (95%CI)

GDM/Control (n)

OR (95%CI)

GDM/Control (n)

OR (95%CI)

Low levels (< 2.30)

36/277

1.000

81/171

3.551 (2.289–5.508)

P < 0.001

3.551 (2.289–5.508)

P < 0.001

0.348 (0.081–0.614)

P = 0.010

2.021 (0.064–3.978)

P = 0.043

High levels (≥ 2.30)

21/127

1.241 (0.694–2.218)

P = 0.466

94/121

5.812 (3.733–9.049)

P < 0.001

4.603 (2.688–7.881)

P < 0.001

OR (95% CI) for high TG levels within category of thyroid function

 

1.241 (0.694–2.218)

P = 0.466

 

1.648 (1.127–2.410)

P = 0.010

 
  1. *Adjusted for age, history of abortion and gravidity
  2. P value < 0.05 was considered statistically significant
  3. GDM Gestational diabetes mellitus, TG Triglyceride, FT3 Free triiodothyronine, FT4 Free thyroxine, RERI Relative excess risk due to interaction, AP Attributable proportion to the interaction