Table 1 Maternal characteristics of women with GDM treated vs. not treated with myoinositol
Patients treated with myoinositol N= 150 | Patients not treated with myoinositol N= 180 | p | |
|---|---|---|---|
Mean ± SD | Mean ± SD | ||
Age at GDM diagnosis (years) | 32.6 ± 5.78 | 32.1 ± 5.48 | 0.412 |
Pregestational BMI (Kg/m2) | 28.8 ± 6.63 | 28.1 ± 6.37 | 0.266 |
Pregestational weight (Kg) | 75.3 ± 18.2 | 73.2 ± 18.7 | 0.281 |
HbA1c at GDM diagnosis (%) | 5.34 ± 0.48 | 5.35 ± 0.51 | 0.859 |
Oral glucose tolerance test at GDM diagnosis | |||
Fasting glycaemia (mmol/L) | 95.7 ± 9.81 | 95.1 ± 10.9 | 0.770 |
Glycaemia after 1 hour (mmol/L) | 150.7 ± 36.5 | 163.5 ± 52.1 | 0.172 |
Glycaemia after 2 hours (mmol/L) | 115.8 ± 30.8 | 122.4 ± 37.6 | 0.364 |
Gestational age at GDM diagnosis (weeks) | 21.7 ± 4.92 | 23.6 ± 4.93 | 0.002 |
Weight at delivery (Kg) | 84.1 ± 17.2 | 81.7 ± 17.5 | 0.213 |
Gestational age at delivery (weeks) | 38.4 ± 1.18 | 38.7 ± 0.99 | 0.105 |
Gestational age at start insulin therapy (weeks) | 27.2 ± 5.13 | 27.7 ± 6.15 | 0.721 |
Subjects (%) | Subjects (%) | ||
Pregestational arterial hypertension | 3 (2%) | 9 (5%) | 0.037 |
History of poliabortivity | 35 (23.3%) | 42 (23.3%) | 0.601 |
Primipara | 45 (30%) | 68 (37.7%) | 0.288 |
Multipara | 105 (70%) | 82 (45.5%) | |
BMI category | |||
Underweight (<18.5 kg/m2) | 3 (2%) | 3 (1.6%) | 0.704 |
Normal weight (18.5-24.9 kg/m2) | 44 (29.3%) | 54 (30%) | 0.235 |
Overweight (24.91-29.9 kg/m2) | 52 (34.6%) | 62 (34.4%) | 0.412 |
Obese (>29,9 kg/m2) | 51 (34%) | 61 (33.8%) | 0.817 |
Insulin treatment | 52 (34.6%) | 57 (31.6%) | 0.723 |
• Long-acting insulin alone | 31 (20.6%) | 8 (4.4%) | <0.001 |
• Short-acting insulin alone | 10 (6.6%) | 11 (6.1%) | 0.989 |
• Basal-bolus insulin | 11 (7.3%) | 34 (18.8%) | <0.001 |
Metformin treatment | 5 (3.3%) | 3 (1.6%) | 0.744 |