Table 4 Crude and adjusted associations (ß estimates and 95% confidence intervals) between individual placental variables and child MSEL ELC scores
From: Placental morphology in association with autism-related traits in the EARLI study
Variablea | n | Crude | Model 1b | Model 2c |
|---|---|---|---|---|
ß (95% CI) | ß (95% CI) | ß (95% CI) | ||
Perimeter (cm) | 96 | 0.02 (−0.58, 0.61) | − 0.12 (− 0.67, 0.44) | −0.1 (− 0.66, 0.46) |
Area (cm2) | 96 | −0.01 (− 0.10, 0.07) | −0.03 (− 0.11, 0.05) | −0.03 (− 0.11, 0.05) |
Radius (cm) | ||||
 Minimum | 96 | 0.1 (−1.96, 2.17) | −0.39 (− 2.36, 1.57) | − 0.37 (− 2.34, 1.60) |
 Maximum | 96 | − 0.33 (− 2.15, 1.49) | 0.16 (− 1.55, 1.87) | 0.18 (− 1.53, 1.90) |
 Median | 96 | −0.66 (−4.25, 2.93) | −1.53 (− 4.88, 1.82) | −1.36 (− 4.75, 2.03) |
Umbilical distance from center (cm) | 96 | − 0.34 (− 2.39, 1.71) | 0.28 (− 1.68, 2.24) | 0.28 (− 1.68, 2.24) |
Eccentricity | ||||
 Eccentricity from Geometric center | 96 | 4.56 (−13.56, 22.69) | 4.6 (− 12.19, 21.39) | 4.91 (− 11.91, 21.74) |
 Eccentricity from Umbilical cord | 96 | −0.51 (− 1.48, 0.45) | − 0.41 (− 1.32, 0.50) | −0.39 (− 1.30, 0.52) |
Thickness of traced central slice (cm) | ||||
 Maximum | 93 | − 8.02 (− 20.85, 4.8) | −4.96 (− 17.00, 7.08) | −4.50 (− 16.77, 7.77) |
 Mean | 93 | −8.63 (− 25.17, 7.92) | −5.63 (− 21.17, 9.9) | −5.24 (− 20.92, 10.45) |
Thickness of traced central slice (cm) (Z score) | ||||
 Maximum | 93 | − 2.68 (− 6.97, 1.61) | −1.66 (− 5.69, 2.37) | −1.51 (− 5.61, 2.60) |
 Mean | 93 | −2.24 (− 6.54, 2.06) | −1.46 (− 5.50, 2.57) | −1.36 (− 5.44, 2.72) |
Placental weight (g) | 89 | − 0.03 (− 0.09, 0.03) | −0.03 (− 0.09, 0.02) | −0.03 (− 0.09, 0.03) |
Birthweight: Placental Weight | 88 | −1.08 (− 5.56, 3.40) | − 0.09(− 4.54, 4.36) | 0.07(−4.49, 4.62) |