Table 1 Prevalence and clinical characteristics of patients with severe PPH 

Total number of deliveries, n

1,037,231

1,029,816

1,003,539

1,005,677

976,978

946,065

918,397

-

Patients with severe PPH, n (rate per 1000 deliveries)

3668 (3.54)

4021 (3.90)

4182 (4.17)

4513 (4.49)

4767 (4.88)

5061 (5.35)

5049 (5.50)

 < .0001

Age, n (rate per 1000 deliveries)

32.9 ± 5.3

33.0 ± 5.3

33.3 ± 5.3

33.4 ± 5.4

33.5 ± 5.3

33.3 ± 5.3

33.6 ± 5.4

 < .0001^b

  ≤ 19

30 (2.35)

31 (2.39)

33 (2.54)

35 (2.93)

33 (2.97)

32 (3.23)

34 (3.87)

.3232

 20–24

203 (2.12)

219 (2.40)

190 (2.19)

242 (2.87)

220 (2.68)

254 (3.20)

228 (2.96)

.0135

 25–29

712 (2.43)

744 (2.63)

762 (2.84)

760 (2.90)

823 (3.28)

880 (3.65)

888 (3.80)

 < .0001

 30–34

1217 (3.31)

1322 (3.62)

1354 (3.77)

1452 (3.98)

1528 (4.31)

1697 (4.91)

1614 (4.82)

 < .0001

 35–39

1150 (5.10)

1289 (5.61)

1369 (6.06)

1438 (6.30)

1544 (6.91)

1603 (7.39)

1611 (7.63)

 < .0001

 40–44

325 (7.73)

395 (8.49)

437 (8.81)

550 (10.46)

598 (11.18)

568 (10.90)

628 (12.25)

 < .0001

 45 ≤ 

31 (32.29)

21 (18.82)

37 (29.09)

36 (27.52)

21 (14.99)

27 (17.86)

46 (27.73)

.0247

Mode of delivery, n (% of patients with severe PPH)

 Cesarean delivery

1467 (40.0)

1541 (38.3)

1652 (39.5)

1698 (37.6)

1769 (37.1)

1742 (34.4)

1820 (36.0)

.0002

 Operative vaginal delivery

303 (8.3)

393 (9.8)

381 (9.1)

466 (10.3)

516 (10.8)

563 (11.1)

587 (11.6)

 < .0001

Etiology of PPH, n (rate per 1000 deliveries)

 Uterine atony

1347 (1.30)

1634 (1.59)

1652 (1.65)

1817 (1.81)

1973 (2.02)

2157 (2.28)

2257 (2.46)

 < .0001

 Placenta previa

467 (0.45)

440 (0.43)

462 (0.46)

471 (0.47)

513 (0.53)

512 (0.54)

528 (0.57)

.0001

 Placenta accreta

466 (0.45)

559 (0.54)

585 (0.58)

650 (0.65)

696 (0.71)

780 (0.82)

830 (0.90)

 < .0001

 Placenta previa accreta

97 (0.09)

105 (0.10)

91 (0.09)

110 (0.11)

103 (0.11)

99 (0.10)

91 (0.10)

.6919

 Retained placenta

58 (0.06)

75 (0.07)

103 (0.1)

130 (0.13)

122 (0.12)

134 (0.14)

151 (0.16)

 < .0001

 Placental abruption

635 (0.61)

613 (0.60)

666 (0.66)

675 (0.67)

622 (0.64)

598 (0.63)

528 (0.57)

.2857

 Cases with IUFD

162 (0.16)

178 (0.17)

150 (0.15)

138 (0.14)

132 (0.14)

128 (0.14)

96 (0.10)

.0017

 Uterine rupture

85 (0.08)

86 (0.08)

100 (0.10)

98 (0.10)

83 (0.08)

97 (0.10)

84 (0.09)

.4750

 Uterine inversion

132 (0.13)

102 (0.10)

120 (0.12)

99 (0.10)

98 (0.10)

138 (0.15)

101 (0.11)

.2690

 Cervical laceration

68 (0.07)

54 (0.05)

59 (0.06)

72 (0.07)

94 (0.10)

101 (0.11)

72 (0.08)

.2896

 Vaginal hematoma

253 (0.24)

284 (0.28)

293 (0.29)

305 (0.30)

342 (0.35)

365 (0.39)

324 (0.35)

 < .0001

 Cervical laceration with vaginal hematoma

125 (0.12)

153 (0.15)

139 (0.14)

178 (0.18)

184 (0.19)

205 (0.22)

194 (0.21)

 < .0001

 Amniotic fluid embolism

38 (0.04)

37 (0.04)

44 (0.04)

52 (0.05)

52 (0.05)

57 (0.06)

42 (0.05)

.3209

 Multiple gestation

141 (0.14)

175 (0.17)

173 (0.17)

178 (0.18)

218 (0.22)

228 (0.24)

252 (0.27)

 < .0001