Table 1 Baseline characteristics of study population (n = 370)
Characteristics | Preeclampsia within 7 days (n = 42) | No preeclampsia within 7 days (n = 328) |
|---|---|---|
Maternal age at recruitment (in years), Mean (SD) | 31.2 (5.8) | 31.2 (6.1) |
Gestational age (in weeks), Median (IQR) | 35.3 (33.4—36.1) | 34.1 (31.1—35.9) |
BMI (in kg/m2), Median (IQR) | 27.3 (24.5—31.7) | 27.3 (23.9—32) |
Parity | ||
Nulliparous | 35 (83.3%) | 145 (44.2%) |
Multiparous | 7 (16.7%) | 183(55.8%) |
Smoking status | ||
Current smoker | 2 (4.8%) | 31 (9.4%) |
Never smoker | 24 (57.1%) | 201 (61.3%) |
Previous smoker | 16 (38.1%) | 96 (29.3%) |
Ethnicity | ||
White British | 37 (88.1%) | 295 (89.9%) |
Other | 5 (11.9%) | 33 (10.1%) |
a sFlt-1, Median (IQR) | 4.03 (3.88—4.15) | 3.38 (3.18 – 3.61) |
a PIGF, Median (IQR) | 1.87 (1.72 – 2.07) | 2.40 (2.17 -2.73) |
a sFlt-1/PIGF ratio, Median (IQR) | 2.11 (1.82 – 2.35 | 0.89 (0.56 – 1.44) |
sFlt-1/PIGF cut off | ||
Ratio ≤ 38 | 1 (2.4%) | 256 (78.1%) |
Ratio > 38 | 41 (97.6%) | 72 (21.9%) |