Table 3 Associations between maternal and fetal characteristics and parental decisions
Characteristics | TOP N (%) | COP N (%) | p-value | OR (95%CI) |
|---|---|---|---|---|
Maternal age (mean ± SD) | 32.8 ± 5.9 | 29.9 ± 6.1 | < 0.001 | |
Maternal age (years) | < 0.001 | 2.25 (1.5–3.38) | ||
< 35 | 153 (58) | 149 (75.6) | ||
≥35 | 111 (42.1) | 48 (24.4) | ||
Education | 0.103 | 1.37 (0.94–2.01) | ||
< Bachelor’s degree | 94 (37) | 87 (44.6) | ||
≥ Bachelor’s degree | 160 (63) | 108 (55.4) | ||
Gravidity | 0.029 | 1.52 (1.04–2.22) | ||
Primigravida | 94 (35.6) | 90 (45.7) | ||
Multigravida | 170 (64.4) | 107 (54.3) | ||
Method of conception | 0.717 | 1.35 (0.27–6.74) | ||
Natural conception | 261 (98.9) | 194 (98.5) | ||
ART | 3 (1.1) | 3 (1.5) | ||
Had at least one child | 0.431 | 1.16 (0.8–1.68) | ||
Yes | 125 (47.4) | 86 (43.7) | ||
No | 139 (52.7) | 111 (56.4) | ||
Previous history of abortion | 0.314 | 1.24 (0.81–1.9) | ||
Yes | 74 (28) | 47 (23.9) | ||
No | 190 (72) | 150 (76.1) | ||
Previous history of having a child with an anomaly | 0.584 | 1.25 (0.56–2.81) | ||
Yes | 13 (4.9) | 12 (6.1) | ||
No | 251 (95.1) | 185 (93.9) | ||
GA at diagnosis (weeks), median (IQR) | 20 (11–23) | 21 (12–23) | < 0.001 | 0.77 (0.71–0.84) |
Organ system | < 0.001 | 9.37 (5.51–15.93) | ||
Isolated | 132 (50) | 178 (90.4) | ||
Multiple | 132 (50) | 19 (9.6) | ||
CNS anomalies | < 0.001 | 5.69 (2.77–11.70) | ||
Yes | 36 (27.3) | 11 (6.2) | ||
No | 96 (72.7) | 167 (93.8) | ||
Severity grade | < 0.001 | |||
Lethal | 201 (76.1) | 36 (18.3) | 99.10 (34.07–288.30) | |
Potentially lethal | 59 (22.4) | 90 (45.7) | 11.64 (4.03–33.56) | |
Non-lethal | 4 (1.5) | 71 (36) | ||
Genetic abnormalities | < 0.001 | |||
Yes | 121 (45.8) | 11 (5.6) | 8.37 (4.18–16.77) | |
No | 55 (20.8) | 119 (60.4) | 0.35 (0.22–0.55) | |
Unknown | 88 (33.3) | 67 (34) |