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Table 3 Maternal pre-pregnancy BMI and risks of clinical phenotypes of preterm birth

From: Association of maternal obesity with preterm birth phenotype and mediation effects of gestational diabetes mellitus and preeclampsia: a prospective cohort study

Parameters

Event/N (%)

Spontaneous preterm labor

Event/N (%)

Premature rupture of the membranes

OR (95% CI)

P

OR (95% CI)

P

Pre-pregnancy BMI group

  

0.021

  

< 0.001

 Normal weight (18.5–24.9)

694/30300 (2.29%)

ref.

496/30102 (1.65%)

ref.

 Underweight (< 18.5)

173/6652 (2.60%)

1.19 (0.99 to 1.43)

0.072

110/6589 (1.67%)

1.17 (0.94 to 1.47)

0.159

 Overweight (25.0–29.9)

82/3078 (2.66%)

1.21 (0.94 to 1.55)

0.138

82/3078 (2.66%)

1.62 (1.26 to 2.09)

< 0.001

Obesity (≥30.0)

14/361 (3.88%)

1.98 (1.13 to 3.47)

0.017

12/359 (3.34%)

2.04 (1.08 to 3.86)

0.029

 

Event/N (%)

Medically indicated preterm birth

  

OR (95% CI)

P

  

Pre-pregnancy BMI group

  

< 0.001

   

 Normal weight (18.5–24.9)

803/30409 (2.64%)

ref.

   

 Underweight (< 18.5)

148/6627 (2.23%)

0.87 (0.72 to 1.07)

0.182

   

 Overweight (25.0–29.9)

135/3131 (4.31%)

1.46 (1.19 to 1.80)

< 0.001

   

 Obesity (≥30.0)

19/366 (5.19%)

2.05 (1.25 to 3.37)

0.005

   
  1. Abbreviations: BMI Body mass index, OR Odds ratio, CI Confidence interval
  2. Significant associations and p-values are emphasized in bold font
  3. ORs were adjusted for maternal age, educational level, and assisted reproduction technology