Pregnancy outcomes |
Assessed from start of pregnancy to pregnancy end date |
Live birth |
Preterm delivery (or record of live birth occurring < 37 weeks GA) |
Fetal death/stillbirth (loss at or after 22Â weeks GA) |
Miscarriage a |
Termination (elective or therapeutic) |
Miscarriage or termination (composite endpoint) |
Ectopic pregnancy |
Pregnancy-related events of interest |
Assessed from start of pregnancy to 90Â days post-pregnancy end date |
Maternal sepsis |
Vaginal or intrauterine hemorrhage |
Pre-eclampsia |
Eclampsia |
Pregnancy-related hypertension |
Liver or biliary disease |
Assessed from start of pregnancy to pregnancy end date |
Premature or preterm labor |
Labor protraction or arrest disorders |
Oligohydramnios |
Polyhydramnios |
Intrauterine growth restriction or poor fetal growth |
Gestational diabetes mellitus |
Assessed during period as stated |
Maternal death (from start of pregnancy to 42Â days after delivery date) |
Preterm premature rupture of membranes (from start of pregnancy until 37Â weeks GA) |
Fetal/perinatal distress or asphyxia (from start of pregnancy to 7Â days after delivery) |