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Table 6 True prevalence of medicine use, sensitivity, specific and positive predictive values of each data sources for selected medicine categories

From: Determining antenatal medicine exposures in South African women: a comparison of three methods of ascertainment

    

True Prevalence [%]

Sensitivity [%]

Specificity [%]

Positive Predictive Value [%]

Category

n

Source

Observed

Prevalence [%]

EST

95% CI

EST

95% CI

EST

95% CI

EST

95% CI

A06: Laxatives

16

Self-report

1.65

2.79

1.34; 3.83

15.63

0.02; 71.69

99.98

98.94; 99.99

95.49

97.30; 99.99

12

Clinician record

1.24

0.01

0.01; 0.02

98.61

97.66; 99.36

0.02

0.01; 0.67

13

EDR

1.34

12.66

0.01; 66.07

99.98

98.73; 99.99

94.50

96.28; 99.99

J01: Systemic antibiotics

97

Self-report

10.03

10.86

3.72; 24.82

48.03

23.25; 99.81

99.98

92.71; 99.99

99.67

51.22; 99.90

55

Clinician record

5.69

9.29

2.27; 21.26

95.26

93.41; 97.26

19.27

1.09; 48.60

167

EDR

17.27

45.41

37.04; 99.78

90.14

84.27; 99.94

35.95

0.27; 48.80

N02: Analgesics

505

Self-report

52.22

13.03

0.00; 49.43

98.70

60.18; 99.95

58.95

48.13; 99.55

26.48

0.23; 47.51

21

Clinician record

2.17

4.98

0.26; 18.96

98.50

96.98; 99.99

33.22

0.07; 48.29

190

EDR

19.65

35.17

20.60; 99.38

84.08

80.95; 99.82

24.87

0.25; 48.64

P01: Anti-protozoals (Metronidazole)

71

Self-report

7.34

7.34

1.34; 10.44

83.08

36.14; 99.93

98.95

94.14; 99.99

86.20

51.76; 99.87

32

Clinician record

3.31

20.82

10.95; 67.18

98.14

97.02; 99.98

47.07

0.38; 49.32

44

EDR

4.55

15.68

7.59; 43.35

96.37

95.02; 98.01

25.52

8.25; 47.90

ART 1.st line

404

Self-report

41.78

38.57

35.57; 42.50

94.50

91.46; 97.39

94.35

91.79; 96.82

91.31

88.10; 95.58

265

Clinician record

27.40

66.41

61.21; 71.45

99.33

98.42; 100.00

98.41

96.42; 100.00

374

EDR

38.68

89.55

85.53; 93.24

96.19

94.07; 98.14

93.65

90.92; 97.17

ART 2.nd line

30

Self-report

3.10

2.90

1.76; 4.14

86.70

72.78; 99.99

99.51

98.91; 100.00

83.97

66.65; 99.88

18

Clinician record

1.86

59.12

39.67; 80.80

99.93

99.68; 100.00

95.93

82.53; 100.00

26

EDR

2.69

86.69

69.45; 99.99

99.93

99.54; 100.00

97.46

83.01; 100.00

Vitamins and supplements

759

Self-report

78.49

16.13

0.00; 30.82

81.97

69.33; 96.99

23.04

11.94; 42.87

17.00

2.82; 47.77

815

Clinician record

84.28

99.82

87.06; 99.97

22.55

15.34; 98.78

19.86

0.08; 48.23

173

EDR

17.89

33.33

17.25; 99.11

88.89

84.20; 99.96

36.59

0.03; 48.20

  1. n Number of cases reported in the source, EST Estimates and bounds of the 95% confidence interval. EDR Electronic dispensing record